By MONTAGUE LAisn AND CLARENCE P. ALFREY, Jn. T HE RAPID INDUCTION of experimental riboflavin deficiency in man resulted in the development of a severe anemia which was reversed by riboflavin administration.1’2 In addition to the anemia, the patients developed a deficiency syndrome characterized by sore throat, hyperemia and edema of the pharyngeal and oral mucous membranes, cheilosis, angular ...

Background Pityriasis amiantacea is an uncommon clinical syndrome of the scalp with a particular reaction pattern seen in a number of inflammatory and infectious dermatoses such as seborrheic dermatitis, psoriasis, atopic dermatitis, contact dermatitis, lichen planus, pityriasis rubra pilaris and various superficial pyogenic or fungal infections. The syndromic diagnosis may be established by th...

Atopic dermatitis (AD) is a chronic cutaneous inflammatory disease. Various categories of therapeutic medications are used for treating AD. Omalizumab is a monoclonal anti-IgE antibody that binds to IgE molecules at the high-affinity receptor (FcepsilonRI) binding site. Therefore, omalizumab can be used as a potential new systemic treatment agent for recalcitrant AD patients with elevated IgE l...

Equine Pastern Dermatitis (EPD) is not a single disease, but a cutaneous reaction pattern of the horse. EPD should be considered a syndrome, rather than a diagnosis. Uncovering the underlying etiology prior to treatment is key to minimizing treatment failures and frustration. To achieve a positive therapeutic outcome, treating the predisposing and perpetuating factors is just as important as ad...

We present 7 cases of postsurgical contact dermatitis due to povidone iodine. The diagnosis was based on the clinical manifestations, the history of exposure, the site of the lesions, and the results of patch tests. This type of dermatitis can develop in the area of surgery or at distant sites exposed to povidone iodine during the surgical intervention. Patch tests with 10% povidone iodine in p...

Our understanding of the interactions between normal skin microbiota and the human host has been greatly extended by recent investigations. In their recent study in mBio, A. Gioti et al. (mBio 4[1]:e00572-12, 2013) sequenced the genome of the atopic eczema-associated yeast, Malassezia sympodialis, and compared its gene content and organization with that of Malassezia globosa, a species implicat...

OBJECTIVE To assess the different epidemiological and clinical features of Paederus dermatitis in Najaf province. METHODS This prospective observational study, including the clinical assessment of 87 patients with definitive diagnosis of Paederus dermatitis, who presented to a dermatology clinic in the Najaf province of Iraq, was carried out from April 2006 to April 2007. RESULTS The peak t...

Malassezia is a monophyletic genus of fungi found on the skin of 7 billion humans and associated with a variety of conditions, including dandruff, atopic eczema (AE)/dermatitis, pityriasis versicolor, seborrheic dermatitis, and folliculitis ([1,2]; Figure 1). In immunocompromised hosts Malassezia can also cause systemic infections. There are 14 currently recognized species of Malassezia, eight ...