introduction: ketamine is an agent used broadly for pediatric procedural sedation and analgesia in emergency departments. it has been found to be safe and with a low risk of complications. as choosing between intravenous (iv) and intramuscular (im) injections is a matter of concern, we did comparison between two methods in terms of their efficacy and the rate of complications. methods: this sin...

considering the growing trend of laryngeal surgeries and the need to protect the airway during and after surgery, among several therapeutic regimens to induce sedation, two regimens of propofol-fentanyl and propofol-midazolam were compared in microlaryngeal surgeries. forty asa i-ii class patients undergoing microlaryngeal surgeries and referring routinely for postoperative visits were randomly...

objectives: the aim of the present study was to compare the effects of intranasal ketamine and midazolam on behavior of 3-6 year-old children during dental treatments.   materials and methods: in this randomized cross-over clinical trial, 17 uncooperative children requiring at least two dental treatments were selected and randomly received ketamine (0.5mg/kg) or midazolam (0.2mg/kg) prior to tr...

how to cite this article: hassanzadeh a, aminzadeh v. the comparison between effect of chloralhydrate and diphenhydramine on sedating for electroencephalography. iran j child neurol. autumn 2016; 10(4):25-29. abstract objective electroencephalography (eeg) is the most effective diagnostic tool in distinguishing epileptic seizure. chloral hydrate (ch) is a sedative hypnotic drug, commonly used a...

objective: several medications have been used for sedation in children in dentistry and intra-nasal route has been reported to be an efficient way regarding patient cooperation. the aim of the present study was to compare the changes in physiologic parameters following intra-nasal midazolam and ketamine administration.   methods: in this randomized cross-over double-blind trial, 17 uncooperativ...

BACKGROUND The aim of this study was to assess validation evidence for a sedation scale for dogs. We hypothesized that the chosen sedation scale would be unreliable when used by different raters and show poor discrimination between sedation protocols. A sedation scale (range 0-21) was used to score 62 dogs scheduled to receive sedation at two veterinary clinics in a prospective trial. Scores re...

BACKGROUND: For logistical reasons sedation studies are often carried out in elective surgical patients and the results extrapolated to the general intensive care unit (ICU) population. We question the validity of this approach. We compared the two sedation regimens used in our general ICU in a trial structured to mimic clinical practice as closely as possible. RESULTS: Forty patients were rand...

OBJECTIVES To determine whether bispectral analysis (BIS) changes during nitrous oxide (N(2)O) sedation in anxious children undergoing extraction of primary teeth. METHODS In this prospective study 45, ASA physical status I children, aged between 7 to 12 years and scheduled for primary teeth extraction under N(2)O/O(2) sedation are included. At baseline (T0) and during the sedation procedure ...

BACKGROUND In the intensive care unit (ICU), analgesia and sedation are used to improve the comfort and safety of patients undergoing intensive care therapies. However, continuous administration of sedatives prolongs the time on mechanical ventilation and ICU stay. These adverse effects can be reduced by clear definition of the goals of sedation combined with a sedation protocol. METHODS The ...