BACKGROUND The incidence and prevalence of CNS involvement in SLE remains unclear owing to conflicting results in the published studies. The aim of the study was to evaluate the incidence and prevalence of major definite CNS events in SLE patients. METHODS 370 SLE patients with no previous history of CNS involvement were prospectively evaluated in a tertiary hospital referral center for 3 yea...

OBJECTIVES To adapt and assess the validity and reliability of LupusQoL for use in Chinese patients with systemic lupus erythematosus (SLE). METHODS Debriefing interviews of subjects with SLE guided the language modifications of the tool. The process of adaptation proceeded according to the guideline and pre-testing results of LupusQoL-China. 220 SLE patients completed LupusQoL-China and a ge...

Improvements in the detection of 13C(CO) res­ onances by using polarization transfer techniques, based on long-range coupling constants "7(13C (CO )1H) = 1 ±0.1 Hz (n > 3), are reported. Coupling constants between 13C(CO) and other rare spin-1/2 nuclei have been observed, and longrange 13C (C O )-’H coupling have been traced by two-dimensional (2D ) 13C/'H heteronuclear shift correlations (HETC...

Several new and know 6-(4-substituted phenyl)-4-(4-substituted phenyl)-2-phenyl-6H-1,3-thiazine (or selenazine) (Z4B7, Z4D5, Z4B7' Z4D5') were prepared by the 1,4-Michael addition reaction of chalcone derivatives with thiobenzamide or phenylselenocarboxamide in basic medium (where chalcones was formed Claisen-Schimidt condensation aromatic aldehydes 4-substituted acetophenone presence sodium hy...

BAFF/BLyS, a pivotal cytokine in B-cell development, survival and proliferation, became a trusted target in systemic lupus erythematosus (SLE) more than 15 years ago when the growth factor was shown to be involved in the pathogenesis of both preclinical models and human SLE. 3 Anti-BLyS monoclonal antibody belimumab (BEL) was licensed in 2011 for the treatment of SLE based on the results of the...

Complexes of the oxa-thia macrocycles [18]aneO4S2, [15]aneO3S2 and the oxa-selena macrocycle [18]aneO4Se2 (L) of types [MCl2(L)]FeCl4 (M = Sc or Y) were prepared from [ScCl3(thf)3] or [YCl2(THF)5][YCl4(THF)2] and the ligand in anhydrous MeCN, using FeCl3 as a chloride abstractor. The [MI2(L)]I, [LaI3(L)] and [LuI2(L)]I have been prepared from the ligands and the appropriate anhydrous metal trii...

Mangrove ecosystems play important ecological roles, including the mitigation of global climate change and biodiversity conservation. However, they have received little attention from scientists for research conservation bats general biodiversity. In Vietnam, bat species inhabiting mangroves been relatively unstudied, while this ecosystem is located along country’s coastal zones has declined dr...