In the title compound, C25H21ClN2O2Se, the selena-diazole ring is almost planar [maximum deviation = 0.004 (2) Å], and the adjacent benzene ring is twisted by 50.6 (1)° with respect to this ring.

OBJECTIVE To assess the safety, tolerability, biologic activity, and efficacy of belimumab in combination with standard of care therapy (SOC) in patients with active systemic lupus erythematosus (SLE). METHODS Patients with a Safety of Estrogens in Lupus Erythematosus: National Assessment (SELENA) version of the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score >/=4 (n = 449)...

1 Localization of Neurotrophin Proteins Within the Central Nervous System by Immmunohistochemistry James M. Conner ................................................................................... 3 2 Neurotrophin Immunohistochemistry in Peripheral Tissues Robert A. Rush and Xin-Fu Zhou....................................................... 21 3 Extraction and Quantification of the Neurotroph...

Selena J An ([email protected]) Asha George ([email protected]) Amnesty LeFevre ([email protected]) Rose N.M. Mpembeni ([email protected]) Idda Mosha ([email protected]) Diwakar Mohan ([email protected]) Ann Yang ([email protected]) Joy Chebet ([email protected]) Chrisostom Lipingu ([email protected]) Japhet Killewo ([email protected]) Peter Winch ([email protected]) Abdullah H Baqui ...

OBJECTIVE To evaluate safety, pharmacokinetics and pharmacodynamics of anti-interferon (IFN)-γ monoclonal antibody AMG 811 in subjects with SLE without or with lupus nephritis (LN). METHODS In this phase Ib, randomised, multiple-dose escalation study (NCT00818948), subjects without LN were randomised to subcutaneous AMG 811 (6, 20 or 60 mg) or placebo and subjects with LN were randomised to s...

BACKGROUND The relationship between cell-bound complement activation products (CB-CAPs: EC4d, EC3d), anti-C1q, soluble complement C3/C4 and disease activity in systemic lupus erythematosus (SLE) was evaluated. METHODS Per protocol, at baseline all SLE subjects enrolled in this longitudinal study presented with active disease and elevated CB-CAPs. At each monthly visit, the non-serological (ns...

Selen je važan mikroelement u prehrani ljudi i hranidbi životinja. Cilj ovoga rada prikazati metode/postupke koji se poduzimaju procesu obogaćivanja janjećeg mesa selenom. Različitim hranidbenim modifikacijama moguće značajno promijeniti (prije svega poboljšati) sadržaj minerala janjećem mesu pa tako selena. Unos selena janjadi varira zbog promjene elementarnog sastava biljnih vrsta tijekom sez...