background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

newborns’ bacterial infections due to group b streptococcus (gbs) happen in two forms including early-onset disease or late-onset disease. in this paper, we report a case of early-onset gbs infection in a male infant. a 22-year-old primigravid woman delivers a term normal looking male infant. nasal flaring, grunting, and poor feeding presented soon after birth. an empiric treatment with intrave...

hyperpigmentation over face in a neonate is rare and the differentials for the same are also rare. congenital chickengunya, fungal and viral infections, drug rash are few differentials. chikungunya virus (chikv) infection manifesting in neonates is very rare. the prevalence of the entity was described only recently. we describe a neonate with hyperpigmentation on day 3 of life with stormy cours...

Background & aim: Sepsis is a major cause of neonatal mortality in the developing countries. The prevention and management of this infection require informed workforce and availability of necessary resources and equipment. Regarding this, the present study was conducted to investigate healthcare workers’ neonatal sepsis knowledge; prevention and management strategies in use for the control of t...

Background: Sepsis or blood stream infection is a clinical lethal syndrome with severe systemic inflammatory response to infection, if not treated quickly, is associated with dangerous consequences and high morbidity and mortality. The traditional and conventional method for identification of sepsis is blood culture method which is so time-consuming and long that it eliminates the possibility o...

Background: Neonatal sepsis is a major cause of mortality and morbidity, especially in developing countries. The goal of the present study was to determine the bacterial etiology and antibiotic sensitivity patterns of neonatal sepsis. Methods: This cross sectional study was conducted on 208 neonates admitted with clinically suspected sepsis over a period of 30 months. Sepsis was divided into ea...

Background Neonatal sepsis is one of the most critical illness in neonates that is responsible for a great proportion of morbidity and mortality in neonates so early diagnosis and identification of high risk cases is a challenging aim of our study. The purpose of this study was to investigate the prognostic value of red cell distribution width (RDW), in neonatal sepsis at the time of admission ...

materials and methods the level of plasma il-6 and blood culture were checked in all the term neonates suspicious to sepsis admitted to the neonatal intensive care unit of shahid beheshti hospital of kashan during 2010-2011. positive blood culture was considered as definite sepsis and negative blood culture as suspicious sepsis. then, the level of il-6 was compared with the state of blood cultu...

background one of the main components involving in the pathogenesis and prognosis of sepsis and septic shock is natriuretic peptide. hemodynamic changes in sepsis or septic shock might explain increased plasma levels of these peptides circulations. objectives the present study aimed to assess the value of brain natriuretic peptide (bnp) in prediction of sepsis state and its related morbidity. w...

case presentation we describe a case of a previously healthy child who presented with sepsis due to varicella gangrenosa. while she initially responded well to a conservative antibiotic and acyclovir treatment, her subsequent rapid deterioration required urgent and repeated debridement. conclusions this report highlights the significance of prompt diagnosis and early surgical intervention for m...