Water in pharmaceutical industry is a key ingredient in many industrial processes, including machine washing and preparation of most medicinal products. The process of regular monitoring for the microbiological quality of water at the points of use is a critical aspect in ensuring the compliance to the limit. However, the full value of the microbiological control could be accomplished by the us...

Statistical experimentation IS the key to make the process robust to environmental noises, to produce the products ~t a lower cost and to enhance the productivity. Analysis of means and dispersions are rational extensions of the Shewhart control chart for comparing products from different design configurations in off-line quality improvement. In this article, we utilize these graphical procedur...

This paper presents an on-line Statistical Process Control (SPC) technique, based on a Generalized Likelihood Ratio Test (GLRT), for detecting and estimating mean shifts in autocorrelated processes that follow a normally distributed Autoregressive Integrated Moving Average (ARIMA) model. The GLRT is applied to the uncorrelated residuals of the appropriate time-series model. The performance of t...

BACKGROUND Those working in healthcare today are challenged more than ever before to quickly and efficiently learn from data to improve their services and delivery of care. There is broad agreement that healthcare professionals working on the front lines benefit greatly from the visual display of data presented in time order. AIM To describe the run chart-an analytical tool commonly used by p...

A SAS macro for performing Analysis of Means (ANOM) type randomization tests for testing the equality of I variances is presented. Randomization techniques for testing statistical hypotheses can be used when parametric tests are inappropriate. Suppose that I independent samples have been collected. Randomization tests are based on shuffles or rearrangements of the (combined) sample. Putting eac...

In recent years, reputation management schemes have been proposed as promising solutions to alleviate the blindness during peer selection in distributed P2P environment where malicious peers coexist with honest ones. They indeed provide incentives for peers to contribute more resources to the system and thus promote the whole system performance. But few of them have been implemented practically...

AN APPLICATION OF THE CONTROL CHART METHOD TO THE ANALYSIS OF FISHERIES DATA IN a paper now in press as a Bulletin of the U. S. Fish and Wildlife Services the writer has discussed the downward trend of the catch of Columbia River Chinook salmon since 1920 and has stated that the decline is doubtless an indication that the runs of this species are seriously depleted. Recently the same data have ...

The organization of genomic sequences is dynamic and undergoes change during the process of evolution. Many of the variations arise spontaneously and the observed genomic changes can either be distributed uniformly throughout the genome or be preferentially localized to some regions (hot spots) compared to others. Conversely cold spots may tend to accumulate very few variations or none at all. ...

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