نتایج جستجو برای: short tandem repeat strs
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In 10,844 parent/child allelic transfers at nine short-tandem-repeat (STR) loci, 23 isolated STR mismatches were observed. The parenthood in each of these cases was highly validated (probability >99.97%). The event was always repeat related, owing to either a single-step mutation (n=22) or a double-step mutation (n=1). The mutation rate was between 0 and 7 x 10(-3) per locus per gamete per gene...
This study is part of an ongoing project aiming at determining the ethnogenesis of an eastern Siberian ethnic group, the Yakuts, on the basis of archaeological excavations carried out over a period of 10 years in three regions of Yakutia: Central Yakutia, the Vilyuy River basin and the Verkhoyansk area. In this study, genetic analyses were carried out on skeletal remains from 130 individuals of...
Different genomic technologies have been applied to cell line authentication, but only one method (short tandem repeat [STR] profiling) has been the subject of a comprehensive and definitive standard (ASN-0002). Here we discuss the power of this document and why standards such as this are so critical for establishing the consensus technical criteria and practices that can enable progress in the...
X chromosome linked short tandem repeat (STR) are powerful auxiliary systems to genomic STR, they are helpful for differentiating if two women have the same father directly, avoiding some of the ambiguity generated from sibship estimation. This report contains the results of population studies on the X chromosome STR DXS10011, DXS101, DXS6789, DXS7132, DXS8377 and DXS9895 carried out in Taiwan....
The short tandem repeat (STR) systems D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX and FGA were studied in Arabian population samples from Morocco and Syria. No significant deviation from Hardy-Weinberg equilibrium could be observed in either preparation. Comparing the Moroccan and Syrian populations using the program RxC, no simi...
Short tandem repeat (STR) analysis has emerged as the method of choice for testing to resolve specimen source contamination and identity problems that arise in surgical pathology. We studied a series of consecutive cases referred for STR typing during a 5-year period to document the usefulness of the approach and to describe the broadening scope of testing. The series demonstrates that STR-base...
A study was conducted to determine if modern forensic DNA typing methods can be properly employed throughout the world with a final goal of increasing arrests, prosecutions, and convictions of perpetrators of modern day trafficking in persons while concurrently reducing the burden of victim testimony in legal proceedings. Without interruption of investigations, collection of samples containing ...
Genotype polymorphism studies at nine short tandem repeat (STR) loci (D3S1358, FGA, TH01, D7S820, VWA, CSF1PO, D5S818, D13S317, TPOX) were carried out in two Ethnic Groups (Tu, Sala) living in Qinhai, a North-West province of China. All loci were in accordance with Hardy-Weinberg equilibrium (P = 0.05).
AIM To investigate the potential of false inclusion of a close genetic relative in paternity testing by using computer generated families. METHODS 10000 computer-simulated families over three generations were generated based on genotypes using 15 short tandem repeat loci. These data were used in assessing the probability of inclusion or exclusion of paternity when the father is actually a sib...
Patrilineally transmitted Y-chromosomal markers have been shown to resolve forensic cases under certain scenarios where autosomal markers provide limited or inconclusive evidence. Several Y-short tandem repeat (Y-STR) loci have been validated for forensic use, and Y-STR haplotype databases for a number of geographic locations are now available in the literature and online. In this review, examp...
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