Introduction: Learning and memory deficits in some diseases are new subjects of research. Bupropion, as dopamine and noradrenaline reuptake inhibitor and an antidepressant agent, has been previously shown to affect learning and memory processes. This study was designed to test the effect of intra-hippocompal bupropion injection on active avoidance learning task in rats. Methods: Adult male ...

objective: elevated amino acid homocysteine (hcy) levels and insufficient physical activity are the risk factors in alzheimer disease (ad) development. the effect of intermittent aerobic training on memory retention test and thiobarbituric acid reactive substances (tbars) and superoxide dismutase (sod) levels in the dorsal hippocampus of rats which were stimulated with hcy is investigated. meth...

Rats handled between trials during shuttle avoidance training were superior to those not handled on several measures of avoidance learning; handled rats were nonetheless inferior to those receiving one-way training. A second experiment clearly demonstrated that differences between shuttle and one-way avoidance could not be attributed to differences in handling. Furthermore, hypotheses which exp...