PURPOSE: To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS: Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups received occlusive bandages while the first one was treated with 2% silver sulfadiazine and the latter was tr...

Development and optimization of a hydrogel with impregnated silver sulfadiazine was pursued, for antimicrobial topical applications. The selected hydrogel exhibited a homogeneous appearance, with whitish colloration and devoid of any fractures or cracks. The content in impregnated silver sulfadiazine was within established limits (1%, w/w) with a standard deviation of up to 1.28%. The hydrogel ...

The present study deals with the formulation of ethosomal suspension containing silver sulfadiazine, followed by its incorporation into a hydrogel, leading to novel vesicular nano-ethogel sulfadiazine for treatment topical burns. Silver Sulfadiazine ethosomes were prepared hot method suggested Elka Touitou. This was loaded hydrogel made Carbopol 934 in ratio 1:1. chosen as gelling agent it do n...

OBJECTIVE: To determine how the synthetic skin substitute Biobrane® compares to silver sulfadiazine (SSD, Silvadene®) in the treatment of patients with low body surface area partial thickness burns. STUDY DESIGN: Systematic literature review of all English language articles of primary studies published between February 1990 and November 2004. DATA SOURCES: Randomized controlled trials comparing...

aloe vera is a tropical plant belonging to the liliaceae family. it has beneficialeffects in variety of diseases. the aim of this study was to formulate a topical cream from a. vera with wound burn healing effect and to perform its clinical trial. a total of 30 patients (20 males and 10 females in the age range of 20-50 years) with second degree burn wounds on their both hands were selected for...

It was aimed to comparatively evaluate the effects of dressing methods with silver sulfadiazine, povidone-iodine, and saline which have a common use in routine practices for burn injuries. Twenty-eight Sprague Dawley adult female rats were used in this study. All the rats were divided into 4 groups: the control group, the povidone-iodine group, the saline group, and the silver sulfadiazine grou...

Background and aim: Shortening of the duration of wound healing is an attractive subject for investigators in recent years. In this study, the effects of topical phenytoin, silver sulfadiazine, estrogen and their combination on wound healing were evaluated.Materials and Methods: This experimental study was accomplised on 30 male albino rats, which had an approximate wei...

In order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. The commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. The release of therapeutic agents in vitro from medicated sp...

Silver nanoparticles supported on nanoscale silicate platelets (AgNP/NSP) possess interesting properties, including a large surface area and high biocide effectiveness. The nanohybrid of AgNP/NSP at a weight ratio 7/93 contains 5-nm Ag particles supported on the surface of platelets with dimensions of approximately 80×80×1 nm(3). The nanohybrid expresses a trend of lower cytotoxicity at the con...