Medullary disorders can be associated with a sleep apnea syndrome. The present patient developed a sleep apnea syndrome with approximately 25 episodes of apnea or hypopnea during each hour of sleep following a lateral medullary infarction. The presence of predisposing factors and involvement of respiratory centers in the area of the medullary lesion may determine the appearance of sleep apnea w...

Objective: To test a prediction model for sleep apnea based on clinical and sociodemographic variables in a population suspected of having sleep disorders and submitted to polysomnography. Methods: We included 323 consecutive patients submitted to polysomnography because of the clinical suspicion of having sleep disorders. We used a questionnaire with sociodemographic questions and the Epworth ...

OBJECTIVE CHARGE syndrome occurs in approximately 1 in 8500 live births and is diagnosed clinically by combinations of major characteristics: choanal atresia, coloboma, characteristic ears, cranial nerve abnormalities and distinct temporal bone anomalies. More than 50% of children with CHARGE syndrome experience sleep disturbances, with obstructive sleep apnea being one diagnosis. Objectives of...

INTRODUCTION Sleep movement disorders includes mainly periodic limb movement and others. The more frequent breathing disorders are: obstructive sleep apnea-hypopnea syndrome and primary snoring. OBJECTIVE To compare sleep architecture in periodic limb movements and breathing disorders of different severity, and weight their interactions. METHODS We compared sleep architecture in 160 patient...

Sleep is a complex behavioral state that occupies one-third of the human life span. Although viewed as a passive condition, sleep is a highly active and dynamic process. The sleep-related decrease in muscle tone is associated with an increase in resistance to airflow through the upper airway. Partial or complete collapse of the airway during sleep can lead to the occurrence of apneas and hypopn...

It was hypothesized that triazolam might decrease central apneas associated with arousal periods in patients with central sleep apnea by hastening the onset of consolidated sleep. Five male patients, diagnosed as having central sleep apnea on a screening night, participated in a double-blind randomized crossover study of the effect of placebo, 0.125 mg triazolam, and 0.25 mg triazolam on sleep,...

About one half of patients who have essential hypertension have obstructive sleep apnea, and about one half of patients who have obstructive sleep apnea have essential hypertension. A growing body of evidence suggests that obstructive sleep apnea is a major contributing factor in the development of essential hypertension. Despite many patients with obstructive sleep apnea having clear symptoms ...

data extraction primary outcomes were incidence, prevalence, or odds ratio of having osteoporosis, defined as bone mineral density t-score < -2.5 sd. results of 353 articles, 344 articles were excluded, 9 underwent full-length review and data were extracted from 7 studies consisting of 113,558 patients. finally, 3 extracted studies were included in the meta-analysis of osteoporosis. among cohor...

background and objective: higher concentration of systemic inflammatory markers is reported in patients with obstructive sleep apnea (osa). levels of inflammatory markers may be associated with severity of osa. objective of this study was to evaluate the correlation between level of inflammation markers and osa severity. materials and methods: fifty six patients with symptoms and signs of osa f...

obstructive sleep apnea (osa) together with metabolic disorders is common in severely obese patients. weight reduction is considered as a treatment modality in these cases while few of them can succeed in considerable weight loss. here, we present a severely obese man with body mass index of 54 suffered from osa, type 2 diabetes, hypothyroidism, and hypertension. he intentionally lost 80 kilogr...