نتایج جستجو برای: snp

تعداد نتایج: 24338  

ژورنال: :مجله دانشگاه علوم پزشکی ایلام 0
زهرا اکبری zahra akbari gastroentrology and liver diseases research center, shahid beheshti university of medical science, tehran, iranتهران-بزرگراه شهید چمران- ولنجک- بیمارستان طالقانی- طبقه ششم -بخش گوارش و کبد سید رضا محبی seyed reza mohebbi gastroentrology and liver diseases research center, shahid beheshti university of medical science, tehran, iranتهران-بزرگراه شهید چمران- ولنجک- بیمارستان طالقانی- طبقه ششم -بخش گوارش و کبد مهدی منتظر حقیقی mahdi montazer haghighi gastroentrology and liver diseases research center, shahid beheshti university of medical science, tehran, iranتهران-بزرگراه شهید چمران- ولنجک- بیمارستان طالقانی- طبقه ششم -بخش گوارش و کبد محمد یعقوب طالقانی mohammad yaghoob taleghani gastroentrology and liver diseases research center, shahid beheshti university of medical science, tehran, iranتهران-بزرگراه شهید چمران- ولنجک- بیمارستان طالقانی- طبقه ششم -بخش گوارش و کبد محمد امین پور حسین قلی mohammad amin pour hossein gholi gastroentrology and liver diseases research center, shahid beheshti university of medical science, tehran, iranتهران-بزرگراه شهید چمران- ولنجک- بیمارستان طالقانی- طبقه ششم -بخش گوارش و کبد سید محمد حسین کشفی seyed mohammad hossein kashfi gastroentrology and liver diseases research center, shahid beheshti university of medical science, tehran, iranتهران-بزرگراه شهید چمران- ولنجک- بیمارستان طالقانی- طبقه ششم -بخش گوارش و کبد مهسا خوان یغما

چکیده مقدمه و هدف: سرطان کلورکتال سومین سرطان شایع و دومین نوع از سرطان است که بیشترین مرگ های سرطانی را در دنیا به خود اختصاص داده است. آسیب های dna و ناپایداری ژنومی از مهم ترین عوامل ایجاد کننده سرطان کلورکتال می باشند. اگزونوکلئاز1 (exo1) تنها اگزونوکلئاز درگیر در این سیستم می باشد. در این مطالعه به دلیل نقش exo1 و به منظور دستیابی به بیومارکرهای مستعد کننده سرطان کلورکتال به بررسی همبستگی ...

2010
Hiroshi Onuma Yasuharu Tabara Ryoichi Kawamura Takashi Tanaka Jun Ohashi Wataru Nishida Yasunori Takata Masaaki Ochi Kazuya Yamada Ryuichi Kawamoto Katsuhiko Kohara Tetsuro Miki Hideichi Makino Haruhiko Osawa

Insulin resistance is a feature of type 2 diabetes. Resistin, secreted from adipocytes, causes insulin resistance in mice. We previously reported that the G/G genotype of single nucleotide polymorphism (SNP) at -420 (rs1862513) in the human resistin gene (RETN) increased susceptibility to type 2 diabetes by enhancing its promoter activity. Plasma resistin was highest in Japanese subjects with G...

2014
Young-Sup Lee Hyeon-Jeong Kim Seoae Cho Heebal Kim

Best linear unbiased prediction (BLUP) has been used to estimate the fixed effects and random effects of complex traits. Traditionally, genomic relationship matrix-based (GRM) and random marker-based BLUP analyses are prevalent to estimate the genetic values of complex traits. We used three methods: GRM-based prediction (G-BLUP), random marker-based prediction using an identity matrix (so-calle...

Journal: :journal of agricultural science and technology 2015
m. bakooie e. pourjam s. b. mahmoudi n. safaie m. naderpour

linked and/or gene-based molecular markers have been used widely in marker-assisted selection (mas) to differentiate resistant and susceptible genotypes. resistance to meloidogyne spp. in beta vulgaris l. is mediated by a single dominant gene (r6m-1). using allele-specific primers (asps), an snp marker harboring a single nucleotide polymorphism (a/g), linked to the resistance gene was developed...

Journal: :international journal of molecular and cellular medicine 0
sinem yalcintepe canakkale-turkey fatma silan canakkale-turkey servet hacivelioglu canakkale-turkey ahmet uludag canakkale-turkey emine cosar canakkale-turkey ozturk ozdemir canakkale-turkey

background vegf gene has been reported to be related with many diseases and recurrent pregnancy loss in various studies. vegf polymorphisms are risk factors for pregnancy losses, and generally studies report only women’s genetic analyses. to evaluate the association between vegf a c405g, c460t, c936t and c2578a polymorphisms and spontaneous abortion, we studied the genotypes of spontaneously ab...

Journal: :iranian red crescent medical journal 0
effat asdadollahpour medical biotechnology research center, ashkezar branch, islamic azad university, ashkezar, yazd, ir iran maryam daneshpour cellular and molecular endocrine research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, ir iran bahareh sedaghati khayat cellular and molecular endocrine research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, ir iran arsalan hashemiaghdam diabetes research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, ir iran mahsa mohammad amoli endocrinology and metabolism research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, ir iran mostafa qorbani department of community medicine, alborz university of medical sciences, karaj, ir iran

conclusions although we found an association between myh9 gene polymorphism and urinary albumin excretion, the results did not show a significant association between myh9 polymorphism (rs4821481) and risk of dn in iranian diabetic patients. background myosin heavy chain 9 (myh9) gene polymorphisms have been implicated in different types of renal disease, as well as in nephropathy attributed to ...

2013
Chiyong Kang Hyeji Yu Gwan-Su Yi

BACKGROUND Due to the low statistical power of individual markers from a genome-wide association study (GWAS), detecting causal single nucleotide polymorphisms (SNPs) for complex diseases is a challenge. SNP combinations are suggested to compensate for the low statistical power of individual markers, but SNP combinations from GWAS generate high computational complexity. METHODS We aim to dete...

Journal: :acta medica iranica 0
amira hamzaoui department of internal medicine, fattouma bourguiba hospital, monastir, tunisia. rim klii department of internal medicine, fattouma bourguiba hospital, monastir, tunisia. olfa harzallah department of internal medicine, fattouma bourguiba hospital, monastir, tunisia. touhami mahjoub department of internal medicine, fattouma bourguiba hospital, monastir, tunisia. silvia mahjoub department of genetic, university of pharmacology, monastir, tunisia.

to assess the association between polymorphisms of the il-6 -174 g/c and behçet's disease (bd) in tunisian patients. dna was extracted from blood samples taken from 43 tunisian patients and 43 healthy controls. the polymorphisms were analyzed by pcr with the pcr-rflp. no significant association was found between patients and controls concerning polymorphism of il6 -174 g/c between the (allelic ...

Journal: :American journal of physiology. Heart and circulatory physiology 2000
S W Rabkin J Y Kong

We examined the hypothesis that sodium nitroprusside (SNP) produces cell death in cardiomyocytes through generation of H(2)O(2). Embryonic chick cardiomyocytes in culture were treated with SNP, and cell viability was assessed by trypan blue, MTT assay, and fluorescent activated cell sorting (FACS) analysis. SNP for 24 h induced a significant (P < 0.001) dose-dependent loss of cell viability. On...

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