نتایج جستجو برای: snp

تعداد نتایج: 24338  

2012
Li-Yeh Chuang Yu-Da Lin Hsueh-Wei Chang Cheng-Hong Yang

BACKGROUND Possible single nucleotide polymorphism (SNP) interactions in breast cancer are usually not investigated in genome-wide association studies. Previously, we proposed a particle swarm optimization (PSO) method to compute these kinds of SNP interactions. However, this PSO does not guarantee to find the best result in every implement, especially when high-dimensional data is investigated...

Journal: :Journal of animal science 2010
L A Rempel D J Nonneman T H Wise T Erkens L J Peelman G A Rohrer

The ability to identify young females with superior reproduction would have a large economic impact on commercial swine production. Previous studies have discovered SNP associated with economically important traits such as litter size, growth rate, and feed intake. The objective of this study was to test for association of candidate SNP with sow prolificacy reproductive traits in gilts of a Lan...

2011
Tomaz Curk Gregor Rot Blaz Zupan

SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic approach called interaction analysis. SNPsyn is both a stand-alone C++/Flash application and a web ...

2017
Venkatesh Vaidyanathan Vijay Naidu Nishi Karunasinghe Anower Jabed Radha Pallati Gareth Marlow Lynnette R Ferguson

Prostate cancer (PCa) is one of the most significant male health concerns worldwide. Single nucleotide polymorphisms (SNPs) are becoming increasingly strong candidate biomarkers for identifying susceptibility to PCa. We identified a number of SNPs reported in genome-wide association analyses (GWAS) as risk factors for aggressive PCa in various European populations, and then defined SNP-SNP inte...

2017
Syed Muhammad Shahid Yog Raj Ahuja Zeenath Jehan

Prostate cancer (PCa) is one of the most significant male health concerns worldwide. Single nucleotide polymorphisms (SNPs) are becoming increasingly strong candidate biomarkers for identifying susceptibility to PCa. We identified a number of SNPs reported in genome-wide association analyses (GWAS) as risk factors for aggressive PCa in various European populations, and then defined SNP-SNP inte...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهرکرد - دانشکده علوم پایه 1392

قابلیت دسترسی به آهن یک محدودیت بزرگ برای تولید محصولات به شمار می رود. تنش آهن توسط فاکتورهای بیرونی وابسته به جذب، انتقال و یا مکانیزم های متابولیسمی مانند ph بالا و غلظت بالای در محلول خاک ایجاد می شود. اخیرا گزارش شده است که no می تواند تأثیرات کمبود آهن را کمتر کرده و قابلیت دسترسی به آهن در داخل سلول به وسیله متعادل کردن حالت احیا را افزایش دهد. بنابراین در این تحقیق دو آزمایش در رابطه با...

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه ملی مهندسی ژنتیک وزیست فناوری 1388

بیماری عروق کرونر قلب (cad) از دلائل اصلی مرگ و میر در سراسر جهان است. در بررسی های اخیر که به صورت وسیعی در سطح ژنوم انجام گرفته است snpهای متعددی بر روی کروموزوم 9p21.3 گزارش شده است که با افزایش خطر ابتلا به cad در ارتباطند. از جمله مهم ترین این snpها rs10757274 و rs2383206 می باشند. در این مطالعه ارتباط پلی مورفیسم های rs10757274 و rs2383206 با بیماری cad در 111 فرد مبتلا به cad و 100 فرد ک...

Journal: :Turkish Journal of Fisheries and Aquatic Sciences 2022

The whole genome resequencing was used to develop single nucleotide polymorphisms (SNP) markers for the yellow catfish (Tachysurus fulvidraco). A total of 46 SNP from 129 individuals were selected 5550676 genotyping which distributed on 26 chromosomes. Of SNPs analyzed, 35 conformed Hardy-Weinberg equilibrium. observed and expected heterozygosity these ranged 0.2519 0.771 0.265 0.5018, respecti...

Journal: :Experimental and Therapeutic Medicine 2023

Asthma is a complex disease, often with evident genetic predisposition; for example, the single‑nucleotide polymorphism (SNP) rs7130588 was significantly associated asthma by genome‑wide association study (GWAS). Analysis of 1000 Genomes Project data suggests that there another SNP, rs6592645, in complete linkage disequilibrium and should present same signal GWAS. However, causal SNP mechanism ...

Journal: :Journal of dairy science 2010
G R Wiggans P M VanRaden L R Bacheller M E Tooker J L Hutchison T A Cooper T S Sonstegard

To facilitate routine genomic evaluation, a database was constructed to store genotypes for 50,972 single nucleotide polymorphisms (SNP) from the Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA). Multiple samples per animal are allowed. All SNP genotypes for a sample are stored in a single row. An indicator specifies whether the genotype for a sample was selected for use in genomic ...

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