نتایج جستجو برای: snp

تعداد نتایج: 24338  

تنش خشکی یکی از محدود کننده‌ترین عوامل محیطی در رشد و تولید گیاهان محسوب می‌شود. سدیم نیتروپروساید (SNP) به­عنوان یک تولیدکننده نیتریک‌اکساید (NO) در کاهش تنش اکسیداتیو ناشی از تنش‌های غیرزیستی نقش دارد. به­منظور بررسی اثر محلول‌‌پاشی SNP بر رشد، عملکرد و برخی ویژگی‌های بیوشیمیایی گیاه دارویی سرخارگل در شرایط تنش خشکی، آزمایشی در قالب طرح کرت‌های خردشده در پایه بلوک‌های کامل تصادفی با سه تکرار ...

ژورنال: دامپزشکی 2018

پیشرفت‌های اخیر در توالی‌یابی DNA و الگوریتم‌های محاسباتی منجر به تشخیص SNPهایی با ارزش بالاتر شده است. در این تحقیق از چندین الگوریتم محاسباتی برای بیان تاثیر SNP‌های ژن استروژن رسپتور آلفا (ESRα) بر عملکرد پروتئین در ژنوم گاومیش استفاده شد.در این بررسی از تراشه Affymetrix90KSNP در112 گاومیش خوزستانی استفاده شده است. دو SNP (Argenin43Histedin,Thronin15Alanin) برای ژن ESRα یافت شد. آنالیز اینSN...

Journal: :international journal of molecular and cellular medicine 0
fakhraddin naghibalhossaini department of biochemistry, shiraz university of medical sciences, school of medicine, shiraz, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences)سازمان های دیگر: autoimmune research center, shiraz university of medical sciences, school of medicine,shiraz,iran . hesam ehyakonandeh department of biochemistry, shiraz university of medical sciences, school of medicine, shiraz, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences) alireza nikseresht autoimmune research center, shiraz university of medical sciences, school of medicine, shiraz, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences) eskandar kamali autoimmune research center, shiraz university of medical sciences, school of medicine, shiraz, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (shiraz university of medical sciences)

multiple sclerosis (ms) is a demyelinating neuro- inflammatory autoimmune disease of the central nervous system. genetic predisposition has long been suspected in the etiology of this disease. the association between mthfr polymorphisms and ms has been ivestigated in different ethnic groups. we investigated the association between mthfr c677t and a1298c missense variants and ms in 180 patients ...

Journal: :reports of biochemistry and molecular biology 0
mehran gholamin tel: +98 51 37112343; fax: +98 51 37112343 atena mansouri student research committee , nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran. mohammad reza abbaszadegan medical genetics research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran-division of human genetics, immunology research center, avicenna research institute, mashhad university of medical sciences, mashhad, iran. reza faridhosseini allergy research center, school of medicine, mashhad university of medical sciences, mashhad, iran. farahzad jabbari azad allergy research center, school of medicine, mashhad university of medical sciences, mashhad, iran. afshin shirkani school of medicine allergy and clinical immunology department, blusher university of medical science, blusher iran.

background:  the development of allergic rhinitis (ar) is caused by the interaction between genetic predisposition and environmental factors. in this study, the association between gata3 single nucleotide polymorphisms and ar in an iranian population was identified. methods:  this case-control study was performed on 86 patients with ar and 86 healthy subjects. this study aimed to evaluate a pot...

Journal: : 2021

Amaç: Kalpain-10 (CAPN10), Ca+2 bağımlı intrasellüler sistein proteazlar ailesinin atipik bir üyesidir. Birçok dokuda eksprese edilir ve başta insülin sekresyonu aktivitesi olmak üzere çok çeşitli hücresel fonksiyonlar için gereklidir. Tanımlanan ilk Tip 2 diyabet (T2D) yatkınlık genidir. Çalışmamızda Türk popülasyonunda CAPN10 gen polimorfizmleri (SNP-44, -43 -137) ile artmış T2D riski arasınd...

2016
Andrew J. Page Ben Taylor Aidan J. Delaney Jorge Soares Torsten Seemann Jacqueline A. 3 Keane Simon R. Harris

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Journal: :Computational Statistics & Data Analysis 2006
Hansong Wang Daniel O. Stram

Genome-wide association studies are likely to be conducted in large scale in the near future. In such studies, searching over hundreds of thousands of markers for the few ones that are associated with disease brings out the multiple-hypothesis testing problem in its severe form. We explore, in a two-stage design, how the use of false discovery rate (FDR) can alleviate the burden of a prohibitiv...

Journal: :thrita 0
siamak mirab samiee food and drug laboratory research center, ministry of health and medical education, tehran, ir iran; day general hospital laboratory, tehran, ir iran samira mohammadi yeganeh department of biotechnology, shahid beheshti university of medical sciences, tehran, ir iran mahdi paryan department of research and development, production and research complex, pasteur institute, tehran, ir iran houri rezvan day general hospital laboratory, tehran, ir iran ehsan mostafavi department of epidemiology, pasteur institute of iran, tehran, ir iran parvin pasalar department of clinical biochemistry, faculty of medicine, tehran university of medical sciences, tehran, ir iran; department of clinical biochemistry, faculty of medicine, tehran university of medical sciences, enghelab ave., tehran, ir iran. tel: +98-9121776031, fax: +98-2188795813

conclusions simpleprobe® real-time pcr is a fast and accurate technique qualified to detect vkorc1 and cyp2c9 snps. these results encourage taking further steps towards using vkorc1 and cyp2c9 allelic screening to prevent clinical complications due to resistance or sensitivity to warfarin as well as anti-coagulant dose adjustment. results the allelic frequencies for vkorc1 c1173t (cc, ct, tt) w...

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