We studied 5 3 patients with B-cell chronic lymphocytic leukemia (B-CLL) and found mutations of the p53 gene in 15%. Patients with p53 gene mutations were found to have an aggressive form of B-CLL disease characterized by advanced Rai stage, rapid lymphocyte doubling time (LDT), and resistance to chemotherapy. While 27 of 29 treated patients (93%) without p53 mutations achieved a partial remiss...

The aim of the study was to investigate whether interleukin-10 (IL-10) genetic polymorphisms influence this cytokine production as well as the incidence and outcome of diffuse large B-cell lymphoma (DLBCL). The frequency of IL-10(-1082G) allele was found to be higher in 199 patients with DLBCL as compared with 112 control subjects (0.47 versus 0.39, P =.043). Increased serum levels of IL-10 wer...

Honeycomb cordierite-based Mn–Ce/Al2O3 catalysts were prepared by the impregnation method and used for low-temperature selective catalytic reduction (SCR) of NOx with NH3, with and without SO2 and/or H2O in a homemade fixed-bed tubular reactor. The catalyst reached nearly 80% NOx conversion at 100 ◦C in the absence of SO2. However, SO2 reduces the catalytic activity (80% to 72%) of the honeycom...

Over the last three decades, ambient concentrations of sulfur dioxide (SO2) air pollution have declined by approximately 80%. This paper tests whether the 1970 Clean Air Act and its subsequent amendments caused this decline. The centerpiece of this legislation is the annual assignment of all counties to SO2 nonattainment or attainment categories. Polluters face stricter regulations in nonattain...

Previously we demonstrated that sphingosine 1-phosphate receptor 1 (S1PR(1)) played a prominent, but not exclusive, role in enhancing the excitability of small-diameter sensory neurons, suggesting that other S1PRs can modulate neuronal excitability. To examine the potential role of S1PR(2) in regulating neuronal excitability we used the established selective antagonist of S1PR(2), JTE-013. Here...

Sulfur dioxide (SO2), a typical gaseous compound found in the atmosphere, corrodes metals, particularly outdoors. When SO2 adsorbs on the surface electrolyte, it easily dissolves, resulting in the formation of protons (H+) and bisulfite ions (HSO3). The former reduces the pH of the surface electrolyte, which promotes metal dissolution. Silver and copper are commonly used in the electronic compo...

Tapping mode atomic force microscopy (TM-AFM) was used for the investigation of the early stages of atmospheric corrosion of pure copper and pure iron. The information obtained by this method is the change of the topography of the sample surfaces with emphasis on the shape and lateral distribution of the corrosion products grown within the first 1300 min of weathering. Investigations were carri...

In the early 1990s, it was projected that annual SO2 emissions in Asia might grow to 80-110 Tg yr(-1) by 2020. Based on new high-resolution estimates from 1975 to 2000, we calculate that SO2 emissions in Asia might grow only to 40-45 Tg yr(-1) by 2020. The main reason for this lower estimate is a decline of SO2 emissions from 1995 to 2000 in China, which emits about two-thirds of Asian SO2. The...

In this work, we investigated the performance of Ag-alumina catalysts for the SCR of NO with methane in gas streams with a high concentration of SO2, typical of coal-fired power plant flue gas. Agalumina catalysts were prepared by co-gelation and nitric-acid leaching was used to remove weakly bound silver species from the catalyst surface [1, 2]. We found that SO2 has a dramatic inhibitory effe...

BACKGROUND Persistently high sulphur dioxide (SO2) emissions from platinum group metal (PGM) smelting pose a major threat to communities located around smelters. This paper examined SO2 emission trends, emission regulations and residents' perceived health risks from exposures to such emissions at Selous Metallurgical Complex (SMC) PGM smelting facility in Zimbabwe. METHODS SO2 data from roof ...