The anti-tumour natural product cis-solamin has been shown to occur as a mixture two of tetra-epimeric diastereoisomers 1A and 1B, whereas solamin (6) was isolated as a single diastereoisomer; the biosyntheses of 1A/B and 6 are likely to involve enzyme-mediated cyclohydrations of the bis-epoxide acetogenins anti-diepomuricanin A2 and syn-diepomuricanin A1 respectively, where addition of water o...

Three new monotetrahydrofuran annonaceous acetogenins, muricin H (1), muricin I (2), and cis-annomontacin (3), along with five known acetogenins, annonacin, annonacinone, annomontacin, murisolin, and xylomaticin, were isolated from the seeds of Annona muricata. Additionally, two new monotetrahydrofuran annonaceous acetogenins, cis-corossolone (4) and annocatalin (5), together with four known on...

Many of the Annonaceous acetogenins, particularly those containing a bisTHF moiety, exhibit outstanding cytotoxicity and pesticidal activity. Their remarkable structural diversity suggests that a complete chemical library of these compounds should be prepared and systematically screened. We show here several approaches to meet this synthetic challenge using the naked carbon skeleton strategy as...

This research describes photo degradation of direct red 81(5-solamin) in the presence of zinc oxide nano-sized catalyst supported on granule glass under UV light irradiation. The effects of some parameters such as various pH and different atmosphere on photo degradation efficiency were studied. After various experiments it was revealed that among various atmospheres, at neutural medium, oxygen ...