Heavy metal and metalloid poisoning in the environment food has piqued public’s interest since it poses significant hazards to ecological system human health. In food, several metals, including cadmium (Cd), lead (Pb), mercury (Hg), tin (Sn), manganese (Mn), aluminium (Al), metalloids, arsenic (As), antimony (Sb), selenium (Se), pose a severe threat It is of utmost importance detect even minute...

Two paintings, made on aluminium support by Silvio Pasotti (among the major exponents of 1960s Italian pop art) were investigated in a totally non-invasive manner to identify materials used artist. Raman spectroscopy, Fourier-transform infrared spectroscopy (FTIR), visible reflectance and spectrofluorimetry with excitation exploited as molecular analysis techniques, which are particularly suita...

Synthesis and characterization of a polymethine cyanine near-infrared (NIR) fluorophoric label for the derivatization and determination of fatty acids separated by capillary electrophoresis are described. The label contains an aromatic amine functionality, which is used to form a covalent linkage with the analyte. Various linking chemistries are explored, including direct amine–acid condensatio...

Searching of new enantiomerically pure chiral derivatives of xanthones (CDXs) with potential pharmacological properties, particularly those with anti-inflammatory activity, has remained an area of interest of our group. Herein, we describe in silico studies and in vitro inhibitory assays of cyclooxygenases (COX-1 and COX-2) for different enantiomeric pairs of CDXs. The evaluation of the inhibit...

Transthyretin kinetic stabilizers are used as first-line drug therapy for transthyretin amyloid polyneuropathy mostly in patients unsuitable liver transplantation. The two drugs prescribed clinical practice Tafamidis and Diflunisal. European Medicines Agency approved this prescription 2011 2019 American Food Drug Association also registered it the same use. Diflunisal is a non-steroidal anti-in...