One titrimetric and two spectrophotometric procedures have been reported for the determination of albendazole and its tablets. Using titrimetry, the drug was titrated directly with Chloramine-T under acidic conditions using a Methyl Orange indicator. The spectrophotometric procedures involve treating the sample solution with a measured excess of Chloramine-T in an acid medium, followed by an es...

Absorption spectrophotometry has been and still is the industry standard for detection in HPLC. Limit of detection (LOD) and linear dynamic range (LDR) are the primary performance requirements and have driven continuous improvement of spectrophotometric HPLC detectors. Recent advances in HPLC column technology have led to low flow-rate HPLC such as capillary HPLC and nanoflow HPLC and put highe...

UV, first, second and third derivative spectrophotometric methods have been developed for the determination of ezetimibe in pharmaceutical formulation. The solutions of standard and sample were prepared in methanol. For the first method, UV spectrophotometry, the quantitative determination of the drug was carried at 233 nm and the linearity range was found to be 6-16 mug/ml. For the first, seco...

A simple and sensitive spectrophotometric method is proposed for the determination of palladium (II) in ppm level using 4-amino-3-mercapto-6-methyl-1, 2, 4-tirazine (4-H)-5-one, a nitrogen, sulphur and oxygen donor triazine, as the spectrophotometric reagent. In aqueous medium at a pH of 11, Pd(II) forms a light yellow colored complex with the proposed spectrophotometric reagent. The optimum co...

This work is concerned with the development and validation of two accurate, precise and specific spectrophotometric and chromatographic methods for analysis of Phenylepherine (PE), Lidocaine (LC) and Thiomersal (TM) in their ternary mixture and in Chromoderm® solution. The developed spectrophotometric method is the mean centering of ratio spectra (MCR) spectrophotometric method that depends on ...

Acetophenone 2’, 4’dihydroxy semicarbazone [A24DHS], a new analytical reagent is proposed as a sensitive and selective spectrophotometric reagent for Vanadium (V). The reagent A24DHS is synthesized in the laboratory and characterized by NMR, IR and elemental analysis. A selective spectrophotometric method is presented for the trace determination of Vanadium using A24DHS as spectrophotometric re...

to develop a new more accurate spectrophotometric method for detecting monoamine oxidase inhibitors from plant extracts, a series of amine substrates were selected and their ability to be oxidized by monoamine oxidase was evaluated by the hplc method and a new substrate was used to develop a peroxidase-linked spectrophotometric assay. 4-(trifluoromethyl) benzylamine (11) was proved to be an exc...

It is the purpose of the research reported in the present series of papers to establish accurate spectrophotometric procedures for the determination of iron, more particularly for use in biochemical and nutrition studies, but applicable generally to the analysis of biological materials, foods, pharmaceuticals, and chemical reagents. Several calorimetric methods for the determination of iron are...

Abstract: Introduction: Apigenin (4,5,7 Trihydroxyflavone) is a natural compound of flavonoids class, which found in various plant constituents. Since primitive years, has been used as traditional medicine, because it possesses biological functions. Common ayurvedic formulations comprising apigenin are market. Hence quality control preparation covering desirable. Objectives: In present study, p...

Background : We tested the in vitro activity of pleconaril and AG7088 against five numbered human rhinovirus (HRV) serotypes and 46 clinical HRV isolates of undefined serotype recovered from patients with common colds. Antiviral effect of pleconaril and AG7088 were assessed by cytophathic effect (CPE) inhibition assays in Ohio HeLaI cells using microscopic and spectrophotometric methods. Both c...