Background: The fertilizing sperm potential is directly related to its mitochondria activity evaluated by measuring the mitochondrial membrane potential (ΔΨm). The objectives of the present study were to investigate the vitality and mitochondrial membrane potential of sperm in infertile men by the and to assess the correlations between sperm parameters and the level of sperm mitochondrial membr...

Background: Chlamydia Trachomatis (CT) is an obligate intracellular bacteria, that requires living cells to replicate itself and is responsible for lower urinary tract disease in men and women. It can cause urethritis, epididymitis, orchitis and complications such as chronic prostatitis in men. Chlamydia infections may also directly affect male fertility by damaging the sperm, because sperm par...

BACKGROUND Global ubiquitination in human semen has been found to negatively correlate with standard semen parameters, indicating that ubiquitination can be considered a marker of poor semen quality. However, the inclusion of all semen components in the analysis may be misleading on the biological significance of ubiquitination of sperm cells. We have recently demonstrated the variable presence...

BACKGROUND This is the first study to assess the outcome of sperm washing and intrauterine insemination (IUI) cycles in human immunodeficiency virus-positive (HIV(+)) men to determine any predictors of success, as well as evaluating the effect of HIV on sperm parameters. METHODS Semen characteristics were evaluated in 106 HIV(+) men and a control group of 234 HIV(-) men, and the effect of mar...

BACKGROUND Oligoasthenoteratozoospermia (OAT) syndrome is the most frequently seen phenotype in male infertility. Spermatogenesis relies closely on hormone regulation. The aim of this study was to assess the correlation between hormone profile and semen parameters in infertile men with idiopathic or varicocele-related OAT syndrome. We tried to illustrate the correlative factors for better semen...

conclusions our findings indicated that oxidative stress could play an essential role in male infertility caused by varicocele and may impair spermatogenesis leading to infertility. objectives in the current study, we aimed to assess the tac (total antioxidant capacity) and mda (malondialdehyde) as stress oxidative markers in infertile men with varicocele and fertile men, and moreover, their co...

OBJECTIVE The effects of dietary fish oil on semen quality and sperm fatty acid profiles during consumption of n-3 fatty acids as well as the persistency of fatty acids in ram's sperm after removing dietary oil from the diet were investigated. MATERIALS AND METHODS In this experimental study, we randomly assigned 9 Zandi rams to two groups (isoenergetic and isonitrogenous diets): control (CTR...

conclusions the results of the present study indicate the protective effects of melissa officinalis on some sperm parameters and spermatogenesis quality in rats exposed to lead. background some medicinal plants with their antioxidant properties have protective effects on sperm parameters and neutralize the harmful effects of lead exposure. objectives the present study aimed to determine the eff...

Objective(s): Melatonin, an important hormone secreted by the epiphysis, is a powerful anti-oxidant with a high potential to neutralize medical toxins. The goal of this study was to demonstrate the beneficial effect of melatonin on epididymal sperm and reproductive parameters in mice treated with acetylsalicylic acid (ASA). Materials and Methods: Male adult mice were divided into four treatment...

BACKGROUND Treatment of differentiated thyroid cancer usually consists of a total thyroidectomy followed by one or several courses of radioiodine ((131)I). (131)I is known to have deleterious effects on radiation sensitive tissues and irradiation to the testes has been shown after its administration. We investigated effects of such treatment on sperm DNA in a patient with differentiated thyroid...