Spinal cord injury induces the disruption of blood-spinal cord barrier and triggers a complex array of tissue responses, including endoplasmic reticulum (ER) stress and autophagy. However, the roles of ER stress and autophagy in blood-spinal cord barrier disruption have not been discussed in acute spinal cord trauma. In the present study, we respectively detected the roles of ER stress and auto...

Introduction: Nasopharyngeal carcinoma is one of the most common malignancies in the head and neck region and radiotherapy is its treatment of choice. In spite of the fact that it is widely used, due to the presence of many sensitive organs or tissues in this region, patients may suffer from a wide range of side effects. One such sensitive tissue is the spinal cord. If the absorbed dose to spin...

     The overall goal of this study was to identify the appropriate biomaterials able to facilitate the regeneration in rat's injured adult spinal cord. Acute damage to axons is manifested as a breach in their membranes, ionexchange distortion across the compromised region, local depolarization and even conduction block. It would be of particular importance to interrupt the progress of events h...

Bone loss after spinal cord injury leads to increased fragility of bone and subsequent risk for low-trauma fractures in the sublesional parts of the body. Although in such injuries upper limbs are normally innervated, bone loss may occur in the upper extremities. The present study was designed to determine the systemic effects of spinal cord injury on the fracture healing of upper limbs in rabb...

Introduction: Today, clinicians and neuroscientists need to have a comprehensive survey of neurological pathologies and injuries. For the First-time, SEEP contrast and Spin-Echo pulse sequences was used for functional imaging of the Lumbar spinal cord. This method used by several research groups for Spinal cord mapping, but other researchers tried to improve BOLD fMRI to Spina...

Background: Cervical spinal cord is important and radiosensitive. It is the most critical organ for the head and neck (H&N;) cancer patients during radiotherapy. If the delivered dose to the cord is more than tolerance dose, demyelination may occur. Objective: Current study aims to analyze the post radiotherapy status of cord in the H&N; cancer patients.Material and Methods: In this a...

Background & Aim: Disabilities resulting from road accidents, especially spinal cord injury, which often occur in the early or middle ages of life, cause psychiatric symptoms and worsen the quality of life in these people. The present study aimed to determine the role of depressed mood in the quality of life of patients with spinal cord injury in Guilan Province (in the north of Iran)...

A spinal cord injury is an uncommon discovery in a clay-shoveler’s fracture. Multiple syncope could be caused by bradycardia which followed injury. These combination findings adds its rarity. This case report aim to share awareness among physicians of the rare complication and management. descriptive also narratively review other literature. Physicians should aware SCIWORA (Spinal Cord Injury W...