spinal cord injured (sci) patients have sexual disorders including erectile dysfunction (ed), impotence, priapism, ejaculatory dysfunction and infertility. treatments for erectile dysfunction include four steps. step 1 involves smoking cessation, weight loss, and increasing physical activity. step 2 is phosphodiesterase type 5 inhibitors (pde5i) such as sildenafil (viagra), intracavernous injec...

spinal cord injury (sci) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. to date, there is no definite treatment for repairing damaged spinal cord tissue. in this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, schwann cells,...

background and aim: the normal response of h-reflex depression (hd) was reduced in chronic spinal cord injury (sci) patients. the reduction of this normal response can lead to increase the muscle tone and spasticity. the purpose of this study is to investigate the effect of tripolar cathodal stimulation on hd in sci patients.   materials and methods: this study was conducted in 10 volunteered s...

introduction family caregivers are often responsible for providing significant support to relatives who require care at home. however, evidence suggests that family caregivers have limited information, resources or support to prepare them for such a role. furthermore, family caregiving can be associated with negative physical and psychosocial outcomes. this study examines the short-term impact ...

introduction: various neuroregenerative procedures have been recently employed along with neurorehabilitation programs to promote neurological function after spinal cord injury (sci), and recently most of them have focused on the acute stage of spinal cord injury. in this report, we present a case of acute sci treated with neuroprotective treatments in conjunction with conventional rehabilitati...

The initial experience concerning the use of magnetic resonance imaging in 94 patients who had sustained chronic cord injury showed its specific advantages over traditional imaging modalities. A variety of 84 cord abnormalities were identified including myelomalacia in 47%, cord cysts in 37%, focal atrophy in 11 % and cord transection in 5%. Canal stenosis was seen in twenty-five patients, ...

spinal cord injury (sci) in humans remains a devastating and incurable disorder. a very important obstacle in axonal regeneration after spinal cord injury is astroglial scaring. the use of self-assembling peptide nanofiber, a hydrogel mimicking extracellular matrix, has been suggested as a scaffold for spinal cord regeneration and inhibition of astrogliosis. however, neurogenesis potential of l...

We investigated whether imatinib (Gleevec®, Novartis), a tyrosine kinase inhibitor, could improve functional outcome in experimental spinal cord injury. Rats subjected to contusion spinal cord injury were treated orally with imatinib for 5 days beginning 30 minutes after injury. We found that imatinib significantly enhanced blood-spinal cord-barrier integrity, hindlimb locomotor function, senso...

1. Gunduz H, Binak DF. Autonomic dysreflexia: an important cardiovascular complication in spinal cord injury patients. Cardiol J. 2012;19:215–9. 2. Phillips AA, Ainslie P, Krassioukov AV, Warburton DE. Regulation of cerebral blood flow after spinal cord injury. J Neurotrauma. 2013;30:1551–63. 3. Abrams G, Wakasa M. Chronic complications of spinal cord injury. UptoDate; 2013. 4. Karlsson AK. Aut...

STUDY DESIGN A prospective analysis evaluating neurologic outcome after early versus late surgery for cervical spinal cord trauma. OBJECTIVES The study was conducted to determine whether neurologic and functional outcome is improved in traumatic cervical spinal cord-injured patients (C3-T1, American Spinal Injury Association grades A-D) who had early surgery (<72 hours after spinal cord injur...