Solar lentigines are benign, brownish lesions that occur on light exposed skin surfaces from age 30 onwards, as a sign of photoaging. As they are of cosmetic importance to many patients, different therapeutic modalities have been tried to remove these unwanted spots. The recent development of short-pulsed, pigment-specific lasers has enabled physicians to selectively destroy the pigment within ...

Fas (CD95, APO-1, TNFRSF6) is a TNF receptor superfamily member that directly triggers apoptosis and contributes to the maintenance of lymphocyte homeostasis and prevention of autoimmunity. Although FADD and caspase-8 have been identified as key intracellular mediators of Fas signaling, it is not clear how recruitment of these proteins to the Fas death domain leads to activation of caspase-8 in...

Most empirical work on color constancy is based on simple laboratory models of natural viewing conditions. These typically consist of spots seen against uniform backgrounds or computer simulations of flat surfaces seen under spatially uniform illumination. In this study measurements were made under more natural viewing conditions. Observers used a projection colorimeter to adjust the appearance...

The functional and cost advantages of Internet telephony are evident. By today's technical standards, however, Voice Over IP (VoIP) is still less secure than traditional telephony. At the same time, the hacker scene is constantly looking for new weak spots and developing ingenious methods of attack to gain access to confidential information and penetrate further into the network.

Bowtie aperture antennas are known to generate sub-diffraction limited optical spots in the visible and near-infrared frequencies, which can be applied to many areas. Regular bowtie apertures fabricated by FIB suffer from tapered sidewall and rounded corner, which degrade its optical enhancement and localization. In this work, a new fabrication method is demonstrated to manufacture bowtie apert...