lichenoid reactions represent a family of lesions with different etiologic factors and a common clinical and histologic appearance. lichen planus is included with lichenoid reactions and is a relatively common chronic mucocutaneous disorder. the most important complication of lichenoid reactions is the possibility of malignant transformation. that is why it has been considered a precancerous co...

background and objective: esophageal cancer especially squamous cell carcinoma (scc) is one of the most common gastro intestinal malignancies in north part of iran (khorasan). the standard treatment for esophageal cancer is surgical resection, but its outcome remains poor. then, the oncologists try to treat this cancer with sandwich protocols especially neo-adjuvant chemo-radiotherapy. several ...

background and objective: human papillomavirus (hpv) is one of the possible etiologic factors  in development of esophageal squamous cell carcinoma (escc). in this study we aimed to study the  role of hpv in escc. patients and methods:in this study, 140 cases of escc were analyzed for the hpv dna by  polymerase chain reaction (pcr) using gp5+/gp6+ primers for l1 open reading frame (orf) to  am...

background: esophageal squamous cell carcinoma (escc) is one of the lethal cancers with a high incidence rate in asia. many genes including cyclin d1 and p16 play important role in its carcinogenesis. we aimed to analyze the expressions of cyclin d1 and p16 with the various clinicopathological characteristics of escc.   method: we examined 30 biopsy samples of escc for cyclin d1 and p16 protein...

objective(s): variation in microsatellite sequences that are dispersed in the genome has been linked to a deficiency in cellular mismatch repair system and defects in several genes of this system are involved in carcinogenesis. our aim in this study was to illustrate microsatellite dna alteration in esophageal cancer. materials and methods: dna was extracted from formalin fixed paraffin embedde...

introduction: the human papilloma virus (hpv) can play a role in the development of head and neck squamous cell carcinoma (scc). our aim was to assess the prevalence of hpv dna in scc of the larynx. the impact of hpv infection on patient survival was also evaluated.  materials and methods: this case-control study was performed in 44 patients with scc of the larynx (case group), while the contro...

introduction: squamous cell carcinoma (scc) is the most common head and neck malignancy. smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. the aim of this study was determining the incidence of etiologic factors in head and neck scc.  materials and methods: this is a cross-sectional su...

human papillomavirus (hpv) dna has been identified in esophageal carcinomas. however, the incidence of hpv varies significantly in different geographical locations. in this study, neoplasms from turkmen sahra, a region in golestan province in northeast part of iran, with a high incidence of squamous cell carcinoma were analyzed for the presence of hpv dna. turkmen sahra is located in the cancer...

background: although color doppler ultrasonography (cdus) is useful in the diagnosis of various diseases of the head and neck, flow signals in oral malignant masses are less studied; hence the present study assesses the usefulness of color doppler ultrasonography in quantifying oral squamous cell carcinoma (oscc) vascularization. in addition, we determine the hemodynamic parameters by spectral ...

background: oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ing1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. the objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...