Unlike the primary tracheal tumors, squamous cell carcinoma of trachea is common, especially in smokers. This type of tumor has a low rate of survival and it is diagnosed too late on account of late presentation of its signs. The treatment of choice is surgical removal followed by adjuvant radiotherapy; Primary radiotherapy is the appropriate treatment in inoperable cases. In this study, we pre...

Comprehensive identification of potential immune-related genes related to tumor biological behavior and their significance in the treatment head neck squamous cell carcinoma with a messenger RNA (mRNA) vaccine

Purpose:Our primary objective is to detail the incidence, site, and timing of penile squamous cell carcinoma (pSCC) recurrence after inguinal lymph node dissection (ILND).Materials Methods:We p...

pilonidal disease consists of a hair-containing sinus or abscess occurring most frequently in intergluteal cleft. this disease is generally benign. although very uncommon entity, it seems reasonable to be aware of possible malignancy in longstanding cases. we report a case of squamous cell carcinoma in a 52- year-old man, with a prolonged history of pilonidal disease and ulceration since 3 mont...

myiasis is the condition of infestation of the body by fl y larvae (maggots). the deposited eggs develop into larvae, which penetrate deep structures causing adjacent tissue destruction. it is an uncommon clinical condition, being more frequent in tropical countries and hot climate regions, and associated with poor hygiene, suppurative oral lesions, alcoholism and senility. the diagnosis of myi...

Introduction: Squamous cell carcinoma of the scrotum is a rare entity, current incidence being 1 per million males year. It was among first occupational malignancies identified.

Marjolin's ulcer following frostbite is a rare occurrence. Our review of literature revealed that only 23 cases have been reported. In most instances heel is involved and the most common associated malignancy is squamous cell carcinoma.We present a 69-year-old male patient with squamous cell carcinoma arising over a frostbite scar in heel 45 years after cold injury. This case is unique with res...

background : interleukin (il)-4 is a member of t helper 2 (th2) axis produced by t-lymphocyte and mast cell. it has been shown that il-4 expression changes in tumor tissues. the main objective of this study is to investigate the expression of il-4 mrna in patients with laryngeal squamous cell carcinoma (lscc) with or without lymph node involvement. materials and methods: mrna expression of il-4...

β-Catenin acts as a structural protein at cell-cell adherens junctions and as a transcription activator mediating Wnt signal transduction. Altered β-catenin expression has been associated with loss of cell differentiation and acquisition of an invasive phenotype. In the present study, β-catenin expression was compared immunohistochemically between oral squamous cell carcinoma (30 cases) and ver...