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the aim of this study was to ascertain the prevalence of human papillomavirus (hpv) 16/18 in oral squamous cell carcinoma (oscc) and normal oral mucosa in iranian individuals with oscc and their association with various risk factors. the investigation followed a hospital-based case-control design. cases were individuals with diagnosed oscc, age- and sex-matched with controls. sixty-six paraffin...

Introduction:  Carcinoma of the larynx is an extremely uncommon clinical entity in pediatric age. The diagnosis of the laryngeal carcinoma is often delayed due to the low index of suspicion. The factors contributing to delayed diagnosis include the similarity of its symptoms to common benign lesions of the larynx in childhood and difficult examination of the larynx in pediatric patients. ...

Background & objective: The histologic distinction of small cell from non-small cell lung carcinoma and correct identification of all subtypes of lung carcinoma are very important in treatment management. The main method for histologic classification of lung tumors is based on morphology. However, in small bronchoscopic biopsies in par...

Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma (SCC) that occurs preferentially in the upper aerodigestive tract. We present two cases of BSCC, one arising in the conjunctiva and the other arising in a paranasal sinus. Clinical and pathological findings in these two cases, including immunohistochemistry is presented along with brief discussio...

The diagnosis of basosquamous cell carcinoma is controversial. A review of cases of basal cell carcinoma showed 23 cases that had conspicuous areas of squamous cell carcinoma. This was distinguished from squamous differentiation and keratotic basal cell carcinoma by a comparative study of 40 cases of compact lobular and 40 cases of keratotic basal cell carcinoma. Areas of intermediate tumour di...

BACKGROUND P63 is a gene located in chromosome 3q27-29, which has been implicated in regulation of stem cell commitment and promotion of squamous differentiation in various tissues. The aim of this study was to investigate whether there was a correlation between p63 expression, differential diagnosis of lung carcinoma, and prognosis. MATERIAL AND METHODS Immunohistochemical expression of p63 ...

AIMS To determine (1) the detection rate of primary carcinoma of the lung by serological assay of CEA (carcinoembryonic antigen); and (2) whether addition of seroassay of squamous cell carcinoma related antigen before treatment improves detection sensitivity. METHODS A prospective study spanning 27 months was conducted at the University Hospital, Kuala Lumpur. Serum CEA (Abbott IMx) and serum...

The primary tracheal cancers are very rare, and squamous cell carcinoma is its most common form, especially in smokers. Due to the late presentation of symptoms, these tumors are usually diagnosed too late, and thus, they have poor survival. The gold standard protocol for these cancers is surgical excision and adjuvant radiotherapy. Primary radiotherapy is applied for the advanced and inoperabl...