The aim of the present study is to evaluate the validity of the simplified reference tissue model (SRTM) and of Logan graphical analysis with reference tissue (LGAR) for quantification of histamine H1 receptors (H1Rs) by using positron emission tomography (PET) with [11C]doxepin. These model-based analytic methods (SRTM and LGAR) are compared to Logan graphical analysis (LGA) and to the one-tis...

The high-affinity radioligand [(18)F]fallypride (FP) is frequently used for quantification of striatal/extrastriatal D(2/3) receptors and the receptor occupancies of antipsychotics (APs). Its 110 minutes half-life allows long scan durations. However, the optimum scan duration is a matter of debate. This investigation focuses on scan-duration-related effects on simplified reference tissue model ...

In February 2000 the first mission using space-borne single-pass-interferometry was launched – the Shuttle Radar Topography Mission (SRTM). The goal of the mission was to survey the Earth surface and to generate a homogeneous elevation data set of the world with a grid spacing of 1 arcsec. Antennas with two different wavelengths were used: Beside the American SIR-C the German / Italian X-SAR sy...

The 1:50.000 topographic maps present a nominal horizontal accuracy of 20 meters and a nominal vertical accuracy of 10 meters with 90% confidence. The data were in most cases extracted with photogrammetric techniques from aerial stereo-photographs during the 80’s. The usual update rate for these maps ranges from ten to twenty years. The Advanced Spaceborn Thermal Emission and Reflection Radiome...

In this research, Interferometric Synthetic Aperture Radar (IFSAR) and Shuttle Radar Topography Mission (SRTM) data are used to delineate a portion of the Saint Louis Bay watershed (Mississippi). In addition to these two digital elevation databases, the National Elevation Data (NED) and the United States Geological Service’ Digital Elevation Model (USGS-DEM) are also used for delineation. Resul...

We present one of the first studies in which interferometric synthetic aperture radar (InSAR) data from the Shuttle Radar Topography Mission (SRTM) are analyzed with regard to the detectability of ocean surface current variations. The InSAR system of SRTM was designed for high-resolution topographic mapping, using two SAR antennas on a Space Shuttle with a cross-track separation of 60 m. For te...