BACKGROUND Little is known about the impact of meticillin-resistant Staphylococcus aureus on patients with advanced cancer, such as its impact on the quality of life of this vulnerable group. To date, research on meticillin-resistant Staphylococcus aureus in the palliative care setting has had a quantitative focus. AIM The purpose of this study was to explore the impact of a meticillin-resist...

background and objective: vancomycin is frequently the antibiotic of choice for the treatment of infections caused by methicillin-resistant staphylococcus aureus (mrsa). for the last years, the incidence of vancomycin-intermediate s. aureus (visa) and vancomycin-resistant s. aureus (vrsa) has been increased in various parts of the world. the present study was carried out to determine the presen...

conclusions the present study reports on a high rate of multi-drug resistance, the predominance of the frequency of class 1 integron, and the emergence of spa type t790 among iranian staphylococcus aureus strains. the results revealed that the dissemination of multi-drug resistance among staphylococcus aureus isolates may be associated with the presence of integrons. therefore, continuous surve...

conclusion: the outcome of this study show that spa and coa typing are suitable meth­ods for mrsa isolates typing because it is easy to use and interpret them, and that these methods can be useful in infection source detection and its control especially in epidemic situations. result: pcr results showed seven different patterns for staff and five different patterns for patients based on spa gen...

conclusions in our study, inducible clindamycin resistance rate was 4%; so it is necessary to conduct d-test regularly by disc diffusion for this bacterium. resistance to erythromycin, clindamycin, ciprofloxacin and gentamicin was significantly higher in mrsa isolates than methicillin susceptible staphylococcus aureus (mssa), although the methicillin resistance prevalence was low. background st...

there is a growing concern about the application of molecular methods in epidemiological studies of infectious diseases. the objective of this study was to determine the genetic stability of methicillin resistance genes in staphylococcus aureus for the evaluation of resistance strain distribution. one hundred and fifteen s. aureus isolates from patients with staphylococcal infection were collec...

conclusions methicillin-resistant staphylococcus aureus is an increasingly common cause of nosocomial infections. our results are in agreement with those of other studies reporting that a few specialized clones are responsible for most cases of mrsa nasal carriage. in this study, mrsa strains isolated from different wards of hospital were closely related when analyzed by coagulase gene typing. ...

Objective Analyze nasal colonization by oxacillin-sensitive and oxacillin-resistant Staphylococcus aureus in people with HIV/AIDS (PWHA) at days 1 and7 of hospitalization. METHOD A prospective observational study conducted in a hospital in the countryside of the state of São Paulo. Nasal swab samples were collected and analyzed through microbiological identification, at days 1 and 7 of hospit...

This study assessed the in vitro activities of ceftaroline and five comparator agents against a collection of Staphylococcus aureus isolates. Ceftaroline demonstrated potent activity against community-associated methicillin-resistant S. aureus (CA-MRSA) isolates and showed bactericidal activity against vancomycin-intermediate S. aureus (VISA), vancomycin-resistant S. aureus (VRSA), heteroresist...

OBJECTIVES Staphylococcus aureus survives inside eukaryotic cells. Our objective was to assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in comparison with established antistaphylococcal agents acting on the bacterial envelope with a distinct mechanism. METHODS The extracellular (broth) and intracellular (THP-1 monocytes) activities of NZ2114 were co...