introduction: despite achievement to complete remission (cr) with current treatments and new multiple chemotherapeutic agents in acute lymphoblastic leukemia (all) patients, the majority of them still relapse during long-term follow-up. the use of post- remission therapy will reduce early relapse in these cases, but the best option is still debatable. patients and methods: in this retrospective...

Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells). ES like cells forms sharp edge colonies that are immunopositive to pluripotency markers and have differentiation capacity to Ectodermal, Mesodermal and Endodermal layers....

human mesenchymal stem cell (msc) can be isolated from bone marrow (bm) and differentiated into multiple lineages. these properties make them promising tools in cell and gene therapy. up to now, no definite therapeutic intervention for late stages of multiple sclerosis (ms) has been found. we decided to inject ms patients with autologous expanded msc. five patients participated in this ongoing ...

stem cells are undifferentiated cells with the ability of proliferation, regeneration, conversion to differentiated cells and producing various tissues. stem cells are divided into two categories of embryonic and adult. in another categorization stem cells are divided to totipotent, multipotent and unipotent cells. so far usage of stem cells in treatment of various blood diseases has been studi...

introduction there are one million deaths from asphyxia in newborn annually. management of this newborn is only supportive. autologuse stem cell therapy may reduce mortality and long term morbidity. outcome of asphyxiated newborn is related to damage cns cells. stem cells prevent apoptosis and induce repairmen of injured neurons. methods in a review study all article related to three keywords o...

Background: Low-level lasers are used for various medical applications including wound healing and hair loss treatment. Cell Therapy using skin stem cells could be a novel approach to hair transplantation. However, there is no study on the effect of low-level laser on the hair follicle stem cells. So, in this study, we investigated the effect of low level laser irradiation on viability and ROS ...

ever-increasing advances in the field of bioethics have been encouraged by recent developments of biomedical technolo-gies. stem cell research and therapy are among the most promising approaches in medicine of which are raised some ethical chal¬lenges. likewise, the therapeutic potential of stem cell-based therapies created new policy concerns for health care sys¬tems, particularly the issue of...

Objective(s): High-risk neuroblastoma is a childhood cancer with poorprognosis despite modern multimodality therapy. Internal radiotherapy using131I-metaiodobenzylguanidine (MIBG) is effective for treating the disease even if it isresistant to chemotherapy. The aim of this study is to evaluate the safety and efficacyof 131I-MIBG radiotherapy combined with myeloablative high-dose chemotherapyand...