in this paper, the quantitative structure activity-relationship (qsar) of the ccr2b receptor inhibitors was scrutinized. firstly, the molecular descriptors were calculated using the dragon package. then, the stepwise multiple linear regressions (sw-mlr) and the genetic algorithm multiple linear regressions (ga-mlr) variable selection methods were subsequently employed to select and implement th...

Classical step-by-step algorithms, such as forward selection (FS) and stepwise (SW) methods, are computationally suitable, but yield poor results when the data contain outliers and other contaminations. Robust model selection procedures, on the other hand, are not computationally efficient or scalable to large dimensions, because they require the fitting of a large number of submodels. Robust a...

In this paper, the quantitative structure activity-relationship (QSAR) of the CCR2b receptor inhibitors was scrutinized. Firstly, the molecular descriptors were calculated using the Dragon package. Then, the stepwise multiple linear regressions (SW-MLR) and the genetic algorithm multiple linear regressions (GA-MLR) variable selection methods were subsequently employed to select and implement th...

in this research multiple-regression analysis with stepwise selection method was employed for investigating the effectof vertical building envelopes solar radiation (evr) on cooling energy consumption (e cooling) in residential sector.the high capacity of solar energy in semi-arid climate (shiraz) can provide a part of buildings required energy. dependson house orientations in two directions of...

Quantitative structure-activity relationship (QSAR) models were employed for prediction the activity of P2X7 receptor antagonists. A data set consisted of 50 purine derivatives was utilized in the model construction where 40 and 10 of these compounds were in the training and test sets respectively. A suitable group of calculated molecular descriptors was selected by employing stepwise multiple ...

quantitative structure-activity relationship (qsar) models were employed for prediction the activity of p2x7 receptor antagonists. a data set consisted of 50 purine derivatives was utilized in the model construction where 40 and 10 of these compounds were in the training and test sets respectively. a suitable group of calculated molecular descriptors was selected by employing stepwise multiple ...

BACKGROUND Increasing evidence supports selective/incomplete (SE) or stepwise (SW) instead of non-selective/complete tissue removal for deep carious lesions in vital teeth, mainly as pulpal risks are significantly reduced. Our aims were to analyze the proportion of dentists who utilize SE/SW for deep lesions in permanent teeth and to identify barriers and facilitators of utilizing SE/SW. METH...

In this research multiple-regression analysis with stepwise selection method was employed for investigating the effectof vertical building envelopes solar radiation (Evr) on cooling energy consumption (E cooling) in residential sector.The high capacity of solar energy in semi-arid climate (Shiraz) can provide a part of buildings required energy. Dependson house orientations in two directions of...

A three dimensional quantitative structure activity relationship (3D QSAR) using k nearest neighbor molecular field analysis (kNN MFA) method was performed on a series of arylbenzofuran derivatives as H3-receptor antagonists. This study was performed with 29 compounds (data set) using sphere exclusion (SE) algorithm and random selection method for the division of the data set into training and ...

We present the analysis and design of a Small World VoIP system (SW-VoIP) which is geared towards customers that are communicating with their Small World of social contacts. We use the term Small World to refer to the Peer-to-Peer (P2P) network of a client and his contacts both incoming and outbound. We reconstruct the small world of a user by collecting calling patterns over a configurable per...