OBJECTIVES To evaluate the development of pharmacist-led antimicrobial stewardship activities in English hospitals. METHODS Distribution of an electronic questionnaire to antimicrobial pharmacists or chief pharmacists in National Health Service hospitals in England. RESULTS Since a previous study, in 2005, overall numbers of specialist antimicrobial pharmacists, and their levels of experien...

Antimicrobial resistance is a worldwide threat and a problem with large clinical and economic impact. Antimicrobial Stewardship Programs are a solution to curb resistance development. A problem of resistance is a separation of actions and consequences, financial and clinical. Such a separation makes it difficult to create support among stakeholders leading to a lack of sense of responsibility. ...

Antimicrobial stewardship has been defined as the limitation of inappropriate use of antimicrobials while optimizing the selection, dosing, route, and duration of antimicrobial therapy to maximize clinical cure or prevent infection; limiting unintended consequences, such as emergence of resistance, occurrence of adverse drug events, and selection of pathogenic organisms (such as Clostridium dif...

As a device of argumentative anticipation, prolepsis use generally is considered a positive rhetorical strategy. Turning to the Climate Stewardship Act (CSA) of 2003, this article contributes to our understanding of environmental communication, political argumen­ tation, and rhetorical theory by examining how proleptic miscalculation can actually produce devastating consequences against one’s c...

Inside this Issue 2 Simulation: A Window into the Detonation of High Explosives 3 Modeling of High-Explosive Detonation Performance 5 The Detonation Sandwich 6 Joint DoD/DOE Munitions Technology Development Program—High Explosives 9 New Faces at the Office of Stockpile Stewardship 10 Publication Highlights T you all for your excellent contributions in FY 2011. The Obama Administration and U.S. ...