As an inhibitor of microtubule assembly, combretastatin A-4 (CA-4)-induced biological responses in tumor cells have been well known, but the corresponding changes in nano-biophysical properties were not investigated given the lack of an ideal tool. Using AFM technique, we investigated the alteration of nano-biophysical properties when CA-4-treated tumor cells underwent the different biological ...

 Background: Paraquat (PQ), as the most widely used herbicide in agriculture, induces poisoning in humans and animals mainly through oxidative stress. This study aimed to investigate the protective effects of nano-curcumin compared with curcumin against PQ-induced mitochondrial dysfunction. Materials and Methods: Thirty-six Wistar rats were used in this study. They were separated into 6 groups...

although carbon nanotubes (cnt) have been employed as reinforcements in nanocomposites, presence of nano scale defects such as stone-wales and vacancy defects in carbon nanotubes (cnt) weakens the mechanical properties of these materials. in this paper the effects of defects in cnts on nanocomposite elastic behavior are investigated using molecular dynamics. stiffness matrices of cnt and nanoco...

in this paper, we have studied the electrical properties of the randomly distributed metallic (co and fe) nano/ micro wires on silicon substrate. deposition was carried out potentiostatically into the pores of the track-etch polycarbonate membrane spin coated onto the si substrate. spin coated films were irradiated with 150mev ni (+11) ions at a fluence of 8e7 ions/cm2, followed by uv irradiati...

the free vibration of the lattice cylindrical composite shell reinforced with carbon nano-tubes (cnts) was studied in this study. the theoretical formulations are based on the first-order shear deformation theory (fsdt) and then by enforcing the galerkin method, natural frequencies are obtained. in order to estimate the material properties of the reinforced polymer with nano-tubes, the modified...

⎯ A new micromachining method to fabricate wafer scale, atomically smooth nano-membranes is described. The delicate membrane is supported on a robust silicon microsieve fabricated by plasma etching. The supporting sieve is micromachined independently of the nano-membrane, which is later fusion bonded to it. The transferred thin-film membrane can be dense, porous or perforated according to the a...

This article deals with the mechanical analysis of a fixed-fixed nano-beam based on nonlocal elasticity theory. The nano-beam is sandwiched with two piezoelectric layers through it’s upper and lower sides. The electromechanical coupled equations governing the problem are derived based nonlocal theory considering to Euler-Bernoulli beam assumptions and based on the nonlocal piezoelectricity acco...

The tectorial membrane (TM) is an extracellular matrix situated over the sensory cells of the cochlea. Its strategic location, together with the results of recent TM-specific mutation studies, suggests that it has an important role in the mechanism by which the cochlea transduces mechanical energy into neural excitation. A detailed characterization of TM mechanical properties is fundamental to ...