A general asymmetric Strecker-type reaction is reported, catalyzed by the Lewis acid-Lewis base bifunctional catalyst 1. The reaction of trimethylsilyl cyanide (TMSCN) with various fluorenyl imines, including n-aldimines and alpha,beta-unsaturated imines, proceeds with good to excellent enantioselectivities in the presence of a catalytic amount of phenol as additive (20 mol%) (catalytic system ...

and Concrete Categories The Joy of Cats Dedicated to Bernhard Banaschewski The newest edition of the file of the present book can be downloaded from http://katmat.math.uni-bremen.de/acc The authors are grateful for any improvements, corrections, and remarks, and can be reached at the addresses Jǐŕı Adámek, email: [email protected] Horst Herrlich, email: [email protected] George E....

A method for the synthesis of α-amino acids by direct reductive carboxylation of aromatic imines with CO2 is described. The protocol employs readily available commercial reagents and serves as a one-step alternative to the Strecker synthesis.

The Strecker degradation reaction was evaluated as a means of modifying hemoglobin in vitro, utilizing ninhydrin as a model compound. Ninhydrin led to modification of hemoglobin (when incubated with hemoglobin or red cells) at physiologic temperature and pH. Isoelectric focusing documented the formation of new hemoglobin bands, all with decreased (more negative) isoelectric points that hemoglob...

Semi-synthetic must containing standard nutrients, a phenolic and aromatic fraction extracted from Albariño grapes synthetic precursors of 3-mercaptohexanol (MOH) 4-mercapto-4-pentan-2-one (MMP) were fermented with three different selected commercial S. cerevisiae yeasts. Wines subjected to anoxic aging at 50 °C for 1, 2, 5 8 weeks, their volatile composition was comprehensively determined by t...

Over the past few decades, enantioselective phosphine organocatalysis has evolved rapidly into a highly efficient catalytic strategy for a range of useful reactions. However, as restricted by the traditional catalytic modes, some important reactions, such as asymmetric Strecker-type reactions, have thus far been out of reach of this strategy. Reported herein is an application of enantioselectiv...