recognition of relationship between the present day stress state and fractures is very important in fractured reservoirs. fractures that are parallel or oblique to maximum horizontal stress have more tendencies to tensile deformation and tensile deformed fractures will be more permeable. the dalan formation is one of the main gas reservoirs of iran witch most of the production from this formati...

purpose: to evaluate the effect of vertical prism induced stress on binocular visual evoked potentials. methods: using checkerboard stimulus patterns in two spatial frequencies (sfs) of 0.48 cpd as a low sf and 2.18 cpd as a moderate sf reversing with temporal frequency of 4 hz, the effect of increasing visual stress using vertical prisms of 0, 1, 2 and 3 prism diopters on binocular visual evok...

The endogenous opioid system represents one of the principal systems in the modulation of pain. This has been demonstrated in studies of placebo analgesia and stress-induced analgesia, where anti-nociceptive activity triggered by pain itself or by cognitive states is blocked by opioid antagonists. The aim of this study was to characterize the effect of opioid receptor blockade on the physiologi...

1. Interpret factors affecting the acute and long-term psychological well-being of the critically ill. 2. Design initiatives to prevent agitation, pain, and delirium and the development of post-traumatic stress disorder in intensive care unit (ICU) patients. 3. Design effective strategies to optimize pharmacologically based ICU patient comfort while avoiding therapeutic misadventures. 4. Apprai...

Calcium-calmodulin-dependent protein kinase IV (CaMKIV) phosphorylates the major transcription factor cyclic AMP-response element binding protein (CREB), which plays a role in emotional behavior. Here, CaMKIV knockout mice (CaMKIV(-/-)) were tested in a battery of stress and anxiety-related behavioral tests, to determine if CaMKIV plays a role in emotional behavior. CaMKIV(-/-) exhibited a decr...

Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful conditions. Menthol induces the sensation of cooling by activating TRPM8, an ion channel in cold-sensitive peripheral sensory neurons. Recent studies identified additional targets of menthol, including the irr...

Chronic stress elicits remarkable alterations to the structure and function of several areas of the central nervous system. Nociception is known to be affected by chronic stress and age, although the observations are contradictory. Herein we report that both young and old rats submitted to a chronic unpredictable stress paradigm have reduced nociception in the tail-flick nociceptive test. Moreo...

The role of the opioid system in mediating effects of alcoholism and stress in depression is far from clear. We studied, therefore, the effects of chronic mild stress (CMS) and alcohol drinking on depression-like behavior and nociception in lines of mice selected for high (HA) or low (LA) swim stress-induced analgesia. Compared to the LA mice, the HA animals display up-regulation of opioid rece...

BACKGROUND Regional anesthesia is known to prevent or attenuate the surgical stress response; therefore, inhibiting surgical stress by paravertebral anesthesia might attenuate perioperative factors that enhance tumor growth and spread. The authors hypothesized that breast cancer patients undergoing surgery with paravertebral anesthesia and analgesia combined with general anesthesia have a lower...