The influence of different types of loading intervention on the resulting end-systolic pressure-volume relation (ESPVR) of the left ventricle in situ was investigated in anesthetized open-chest dogs. Left ventricular volume was measured by conductance catheter and pressure was measured by tip-micromanometer. Two loading interventions were applied: a pressure intervention (INp) by gradually occl...

BACKGROUND AND PURPOSE We observed recently that elevated plasma cysteine levels are associated with poor clinical outcome in acute stroke patients. In a rat stroke model, cysteine administration increased the infarct volume apparently via its conversion to hydrogen sulfide (H2S). We therefore investigated the effects of H2S and the inhibition of its formation on stroke. METHODS Cerebral isch...

BACKGROUND Ischemic strokes without a well-defined etiology are labeled as cryptogenic, and account for 30-40% of strokes in stroke registries. The left atrial appendage (LAA) is the most typical origin for intracardiac thrombus formation when associated with atrial fibrillation. Here, we examined whether increased LAA volume detected with cardiac computed tomography (cCT) constitutes a risk fa...

The QRS amplitude, duration, and mean axis direction of the standard 12-lead electrocardiogram were compared with left ventricular mass, volume, wall thickness, and stroke work in 112 adult patients. These patients had normal left ventricles or various degrees of left ventricular dilatation or hypertrophy. Left ventricular volumes and mass were determined by a quantitative angiocardiographic me...

INTRODUCTION Resuscitation with saline is a standard initial response to hypotension or shock of almost any cause. Saline resuscitation is thought to generate an increase in cardiac output through a preload-dependent (increased end-diastolic volume) augmentation of stroke volume. We sought to confirm this to be the mechanism by which high-volume saline administration (comparable to that used in...

Abstract Chronic stroke results in significant downstream changes at connected cortical sites. However, less is known about the impact of on cerebellar structure. Here, we examined relationship between chronic stroke, volume, symmetry, language impairment, and treatment trajectories a large cohort (N = 249) left hemisphere (LH) patients with aphasia, using healthy aging 244) as control data. Ce...

BACKGROUND Left atrial appendage (LAA) volume has been shown to be increased in patients with acute cryptogenic stroke. Atrial fibrillation (AF) is a well-recognized risk factor but it is not the only one associated with LAA enlargement. The aim of the study was to clarify the multifactorial etiology of LAA enlargement in cardiogenic stroke/TIA patients without AF. METHODS Altogether 149 pati...

Stroke has a major impact worldwide in terms of mortality and morbidity. The aim our research was to determine the effect serum Vaspin level on acute ischemic stroke investigate relationship between level, National Institutes Health Scale (NIHSS) infarct volume. This study carried out 100 patients hospitalized with diagnosis Neurology Department Yakutiye Research Hospital Atatürk University Fac...

BACKGROUND AND PURPOSE The purpose of this study was to compare recanalization and reperfusion in terms of their predictive value for imaging outcomes (follow-up infarct volume, infarct growth, salvaged penumbra) and clinical outcome in acute ischemic stroke patients. MATERIAL AND METHODS Twenty-two patients admitted within 6 hours of stroke onset were retrospectively included in this study. ...