PMS55 CoSt-EffECtivEnESS AnAlySiS of StrontiuM rAnElAtE vErSuS AlEndronAtE for MAnAgEMEnt of oStEoPoroSiS AMong PoStMEnoPAuSAl WoMEn in MAlAySiA uSing A MArkov ModElling APProACh Wu D.B.C.1, Hussain S.2, Mak V.1, Lee K.K.C.1 1Monash University Malaysia, Selangor, Malaysia, 2University of Malaya, Kuala Lumpur, Malaysia Objectives: Osteoporotic fractures are common in older adults and are often a...

A cohort of persons exposed in utero due to radioactive contamination of the Techa River (Southern Urals, Russia) in the early 1950s represents a unique opportunity for studying radiation risks from chronic exposures in early life. Bone-seeking strontium radioisotopes were the main contributors to haemopoietic tissue doses received in utero from maternal ingestion of radionuclides before and du...

The distribution of divalent ions in semidilute solutions of high-molecular-mass DNA containing both sodium chloride and strontium chloride in near-physiological conditions is studied by small-angle x-ray scattering and by small-angle neutron scattering. Both small-angle neutron scattering and small-angle x-ray scattering reveal a continuous increase in the scattering intensity at low q with in...

The aim of our study was to investigate how exposure to heavy metal-rich waters from gypsum mining affects the morphology and levels of primary DNA damage in Gammarus balcanicus. Chemical analysis revealed increased concentrations of metals in water and sediment collected at a site impacted by gypsum mine wastewaters. The specimens also showed elevated total tissue metal levels when compared wi...

We report the observation of vacuum ultraviolet (VUV) emission in the region 40 − 560 nm from incandescently heated atomic hydrogen and atomized strontium. Typically the emission of vacuum ultraviolet light from hydrogen gas is achieved using discharges at high voltage, synchrotron devices, high power inductively coupled plasma generators, or a plasma is created and heated to extreme temperatur...

The uranium (234U/238U) and radium (228Ra/226Ra) activity ratios and 87Sr/86Sr isotopic ratio in thermal groundwater, subsurface water (groundwater) and river water from Poddebice and Uniejow were determined. The uranium and radium activity ratios and strontium isotopic ratio varied from 0.629 to 1.471, from 0.396 to 4.961 and from 0.708438 to 0.710344, respectively. The results for the thermal...

A series of zwitterionic hybrid membranes were prepared via the ring opening of 1,3-propanesultone with the amine groups in the chains of TMSPEDA and a subsequent sol-gel process. Their kinetic models for strontium removal were investigated using three two-parameter kinetic equations (i.e., Lagergren pseudo-first order, pseudo-second order, and Elovich models). Adsorption mechanism was evaluate...

Introduction Strontium ranelate is an agent used for the treatment of osteoporosis. It consists of two atoms of stable strontium and an organic part: ranelic acid. Simultaneously, it stimulates the formation of new bone and reduces bone resorption, resulting in a deviation from the balance of bone turnover towards formation. These actions are effected by improving the replication of pre-osteobl...

OBJECTIVE To evaluate changes in the use of strontium ranelate following a health safety warning in November 2007 on the risks of the development of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) with the use of this medicine. METHOD Monthly strontium ranelate DHD (daily defined doses/1,000 inhabitants/day) were calculated between 2006 and 2008 in a health area of Spain. The data w...