The paper introduces a web-based authoring support system, MuTUAL, which aims to help writers create multilingual texts. The highlighted feature of the system is that it enables machine translation (MT) to generate outputs appropriate to their functional context within the target document. Our system is operational online, implementing core mechanisms for document structuring and controlled wri...

Three-dimensional printing is one of the most promising techniques for the manufacturing of scaffolds for bone tissue engineering. However, a pure scaffold is limited by its biological properties. Platelet-rich plasma (PRP) has been shown to have the potential to improve the osteogenic effect. In this study, we improved the biological properties of scaffolds by coating 3D-printed polycaprolacto...

A promising therapy for retinal diseases is to employ biodegradable scaffolds to deliver retinal progenitor cells (RPCs) for repairing damaged or diseased retinal tissue. In the present study, cationic chitosan-graft-poly(ɛ-caprolactone)/polycaprolactone (CS-PCL/PCL) hybrid scaffolds were successfully prepared by electrospinning. Characterization of the obtained nanofibrous scaffolds indicated ...

In this study, we manufacture and analyze bioactive magnesium-calcium silicate/poly-ε-caprolactone (Mg-CS/PCL) 3D scaffolds for bone tissue engineering. Mg-CS powder was incorporated into PCL, and we fabricated the 3D scaffolds using laser sintering technology. These scaffolds had high porosity and interconnected-design macropores and structures. As compared to pure PCL scaffolds without an Mg-...

Two-photon polymerization (2PP) is applied for the fabrication of 3-D Zr-Si scaffolds for bone tissue engineering. Zr-Si scaffolds with 150, 200, and 250 μm pore sizes are seeded with human bone marrow stem cells (hBMSCs) and human adipose tissue derived stem cells (hASCs) and cultured in osteoinductive and control media for three weeks. Osteogenic differentiation of hASCs and hBMSCs and format...

Novel therapies are crucially needed for short bowel syndrome. One potential therapy is the production of tissue engineered intestine (TEI). The intestinal environment presents significant challenges to the selection of appropriate material for tissue engineering scaffolds. Our goal was to characterize different scaffold materials to downselect to that best suited for TEI production. To investi...

The purpose of this paper is to provide an example of an empirical procedure for generating user-based cognitive and social cognitive models of tasks/problems/contexts that can be employed to create readily navigable link structures for virtuality-mediated communication and collaboration purposes. Employing a natural language, user-based method, this study describes patterns found across 128 in...

Chitosan-collagen scaffolds were produced by freeze-drying method and coated with a thermoresponsive polymer poly(N, N-diethylacrylamide) (PDEAAm) to confer them temperature sensitivity using a non residue technology, the supercritical carbon dioxide (scCO2). All native and coated scaffolds were characterized by SEM, intrusion mercury porosimetry, swelling, biodegradability and mechanical analy...

Composite chitosan-nano-hydroxyapatite microspheres and scaffolds prepared using a co-precipitation method have shown potential for use in bone regeneration. The goal of this research was to improve the functional properties of the composite scaffolds by modifying the fabrication parameters. The effects of degree of deacetylation (DDA), drying method, hydroxyapatite content and an acid wash on ...

The mechanical properties of anterior cruciate ligament (ACL) reconstruction scaffolds were evaluated after exposure to functional challenges in vitro: cyclic loading combined with various proteolytic enzymes. Scaffolds were prepared from collagen fibers that were uncrosslinked (UNXL), crosslinked with ultraviolet irradiation (UV), or 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC; 10 or 2...