The terms, acute, subacute, chronic and relapsing types have been used to classify EIA cases. These types have been correlated with clinical and pathological observations. The acute and subacute types have sevet·e clinical symptoms and are often followed by death while the chronic type is identified by the occurrence of intermittent febrile attacks in a sut·viving case of the disease and with m...

Subacute MTX-induced encephalopathy is characterized by an abrupt onset of focal neurologic deficits within days after intrathecal or systemic therapy. Demyelination is one proposed mechanism. We describe the neuroimaging features of 2 patients with clinical symptoms of subacute encephalopathy after intrathecal and systemic MTX therapy. DWI showed restricted diffusion, indicating cytotoxic edem...

PURPOSE OF REVIEW This article describes the background, clinical presentation, diagnosis, and treatment of selected etiologies of subacute and chronic meningitis. Key diagnostic considerations when evaluating a patient presenting with chronic inflammation of the CNS are discussed, and several specific infectious, neoplastic, and autoimmune etiologies are reviewed in detail. RECENT FINDINGS W...

It is common experience that pyogenic osteomyelitis varies in severity from an acute or fulminating illness to a comparatively mild one. Since 1944, when antibiotics, with or without surgical drainage, have been used successfully in treatment, the severely ill patient has been seen less often, and there has been a marked increase in the number of patients presenting with a mild or subacute illn...

Subacute sclerosing panencephalitis (SSPE) is now considered to be caused by measles virus. There are four diagnostic criteria, namely the clinical picture, a characteristic EEG, serology of serum and CSF and brain histology. A register of cases in the U.K. has been kept since 1971, and up to September 1977, ninety-six patients have been reported. The male/female ratio is 2 : 1. The disease mos...

F EVER in a patient with heart disease frequently indicates infection or infarction of either the heart or lung. However, the occurrence of infection and infarction concomitantly in the heart is, at least statistically, extremely uncommon. Only four cases' 3 have been reported in the literature of bacterial invasion of an acute myocardial infarction followed by abscess formation in the myocardi...

F EVER in a patient with heart disease frequently indicates infection or infarction of either the heart or lung. However, the occurrence of infection and infarction concomitantly in the heart is, at least statistically, extremely uncommon. Only four cases' 3 have been reported in the literature of bacterial invasion of an acute myocardial infarction followed by abscess formation in the myocardi...

Respiratory failure is a common complication of acute neuromuscular disease and high cervical cord lesions and should be monitored by measuring forced vital capacity and respiratory rate. Urgent imaging is mandatory if there is any clinical suspicion of spinal cord disease. Treatment of Guillain-Barré syndrome with plasma exchange or intravenous immunoglobulin (IVIg) speeds up the rate of recov...