نتایج جستجو برای: sulfur mustard
تعداد نتایج: 38828 فیلتر نتایج به سال:
Introduction: IFN-γ is one of the most important cytokines in the development of chronic inflammatory diseases such as asthma and COPD. The IFN-γ promoter methylation at CpG islands could be altered by various chemical and toxic substances which may have a role in the incidence of chronic pulmonary diseases and its severity. Thereby, the present study was aimed to evaluate the effect of sulfur ...
Sulfur mustard (SM, bis- (2-chloroethyl) sulphide) is a chemical warfare agent that causes DNA alkylation, protein modification and membrane damage. SM can trigger several molecular pathways involved in inflammation and oxidative stress, which cause cell necrosis and apoptosis, and loss of cells integrity and function. Epigenetic regulation of gene expression is a growing research topic and is ...
Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results
Among the most readily available chemical warfare agents, sulfur mustard (SM), also known as mustard gas, has been the most widely used chemical weapon. SM causes debilitating effects that can leave an exposed individual incapacitated for days to months; therefore delayed SM toxicity is of much greater importance than its ability to cause lethality. Although not fully understood, acute toxicity...
Background: The skin is among the main tissues affected bySulfur Mustard (SM) in chemical attacks. Iranian researchershave performed extensive studies on the exposed victims andhave reported a wide spectrum of information in this field. Themain objective of this study was to develop a comprehensive<sp...
Background: Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. Methods : One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. Of them, 52 cases had been e...
Background and Aim: In breach of all international conventions, Iraq frequently used chemical weapons against both military and civilian targets in its 8-year war with Iran. The most frequently used agent was sulfur mustard. The effects of mustard gas may be divided into early and late categories. Late lesions, due to the agent's mutagenic and carcinogenic potential, are mainly the results of i...
Introduction: Chronic Obstructive Pulmonary Disease (COPD) secondary to sulfur mustard exposure, known as mustard lung, is an important late pulmonary complication. The BODE (Body mass index, Obstruction, Dyspnea, and Exercise) index has been established as a valuable tool for determining the adverse consequences of COPD. The aim of this study was to evaluate the role of the BODE index in pat...
introduction: data on imaging findings in pulmonary complications of chemical agents is scarce. the current study aimed to evaluate radiological findings of late onset pulmonary complications in chemical warfare victims (cwv) and to guide pulmonologists in diagnosis of these subjects. materials and methods: ninety- three male cwv were enrolled in this prospective study, 20-25 years (mean=23) ...
An iron(II)phthalocyanine (Fepc) modified mesoporous titania (Fepc-TiO2) nanocatalyst with a specific surface area of 215 m(2) g(-1) has been synthesized by a hydrothermal method. Fepc-TiO2 degrades one of the highly toxic chemical warfare agents, sulfur mustard (SM), photocatalytically under sunlight with an exposure time of as low as 70 min. Furthermore, the mesoporous Fepc-TiO2 also captured...
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