BACKGROUND With the rapidly increasing application of adaptive radiotherapy, large datasets of organ geometries based on the patient's anatomy are desired to support clinical application or research work, such as image segmentation, re-planning, and organ deformation analysis. Sometimes only limited datasets are available in clinical practice. In this study, we propose a new method to generate ...

Background In recent years liver resection has increasingly been performed. Bleeding and hepatic acute failure, secondary to vascular inflow occlusion (Pringle’s manoeuvre), remain significant complications; these problems seem to be higher in older patients and in those with cirrhosis. Several surgical tools such as CUSA, Harmonic scalpel, Bipolar scissors, Ligasure diathermy, have been develo...

BACKGROUND Opioid substitution therapy (OST) is the most commonly provided treatment for heroin dependence in Australia and has been shown to be effective. Access to OST outside of specialised public clinics and prisons relies on the participation of general practitioners. In Australia there is a shortage of GPs available to prescribe OST, which results in an unmet need for OST services. Studie...

Although surgical excision is the standard of therapy for small renal masses (SRMs), there is a growing recognition of active surveillance as an option in select patients who are poor surgical candidates or who have shorter life expectancy. A number of patients on expectant management, however, subsequently advance to definitive therapy. In this study, we systematically reviewed the literature ...