conclusions symptomatic hyponatremia secondary to siadh remains a rare complication of cryptococcal meningitis. case presentation a 67-year-old male with liver transplantation due to hepatitis c (hcv) related liver cirrhosis developed severe hyponatremia four months after liver transplantation, which was discovered during routine clinic visit. patient was referred to the emergency department, t...

Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) refers to the excessive release of antidiuretic hormone (ADH) resulting in water retention, dilutional hyponatremia and urinary sodium waste, and some other clinical manifestations. Causes of SIADH include many disease conditions, some medications and nicotine. The present study reports a case of psychosis followed by lung canc...

SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION ASSOCIATED WITH SMALL CELLS LUNG CANCER WITH BONE METASTASIS (ABSTRACT): A patient with a bone metastasis developed a asymptomatic hyponatremia, with all features of the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH). The event was interpreted as a consequence of ADH release due to to primary cancer located in the lungs ...

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) may develop in association with several malignancies. However, as an immunohistochemical analysis is not performed in the majority cases, its true cause is often uncertain. We herein report a case of SIADH following chemotherapy due to tumor-derived ADH production in a patient with mucosa-associated lymphoid tissue (MALT) lymphoma...

Although the syndrome of inappropriate ADH secretion (SIADH) has many causes, principally pulmonary, central nervous system or neoplastic disease, and drugs, patients may present with SIADH in whom the etiology is not readily evident. We measured serum ADH levels in such an individual in both the eunatremic and water-loaded states and found levels to be undetectable despite failure to dilute th...

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) has been recognized to occur following treatment with vincristine. None of the reports have provided information regarding its potential for recurrence on further challenge with vincristine (VCR), an agent generally required for repeated use in patients with malignancies. Symptomatic hyponatremia and SIADH that occurred 8 days...

RANKL: Receptor activator of nuclear factorkappa B ligand; PTHrP: Parathyroid Hormone Related Peptide; ACTH: Adrenocorticotropic Hormone; POMC: Pro-Opiomelanocortin; PNES: Paraneoplastic Endocrine Syndrome; OPG: Osteoprotegrin; CS: Cushing’s Syndrome; CLIP: Corticotrophin-Like Intermediate Lobe Peptide; MSH: α-Melanocyte Stimulating Hormone; CLIP: Corticotrophin-Like Intermediate Lobe Peptide; ...

Urea has been recently proposed for the management of hyponatremia linked to the syndrome of inappropriate secretion of ADH (SIADH). The objective of the study was to review the levels of evidence for treatment of hyponatremia associated with SIADH with urea. We performed a: systematic review of experimental trials and grading according to SIGN. No clinical trials were found. The 6 studies anal...

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common disease leading to hyponatremia, and it is characterized by an inappropriately elevated serum ADH level relative to serum osmolality. This syndrome may occur in a variety of clinical settings including malignancies. However, it is rarely observed in association with prostate cancer. Moreover, its pathogenesis an...