We welcome the comments by Nick Freemantle and Domenico Pagano in response to our publication on redevelopment external valida­tion of SYNTAX score II 2020 (SS 2020) for individualised decision making patients with de-novo three-vessel or left main coronary artery disease, both.1Takahashi K Serruys PW Fuster V et al.Redevelopment validation individualise between percutaneous surgical revascular...

The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) score is an invasive coronary angiography (ICA)-based score for quantifying the complexity of coronary artery disease (CAD). Although the SYNTAX score was originally developed based on ICA, recent publications have reported that coronary computed tomography angiography (CCTA) is a feasible modality fo...

BACKGROUND Should the SYNTAX score be integrated in Interventional Cardiology? Should it really be considered as a vital decision-making tool in percutaneous coronary intervention (PCI)? To confirm the importance of this score, we aimed to systematically compare the postinterventional adverse cardiovascular outcomes which were observed in patients who were allotted a low versus a high SYNTAX sc...

BACKGROUND AND OBJECTIVES The aim of this study was to examine the hypothesis that pentraxin 3 (PTX3) can have a diagnostic value for predicting anatomical complexity of coronary artery stenosis as measured by the Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) score. SUBJECTS AND METHODS We investigated the association of systemic arterial PTX3 with SYNTAX score among 500 patient...