In this case of secondary syphilis, pustular lesions progressed rapidly to painful ulcerative lesions in a patient with early HIV infection. This rapidly progressive form of early syphilis has historically been called lues maligna praecox, a severe form of noduloulcerative secondary syphilis. Serologic tests for syphilis were positive and biopsy showed forms consistent with Treponema pallidum i...

Editorials 158 The adverse impact of syphilis on child health has been known for over 500 years, yet the World Health Organization (WHO) only targeted congenital syphilis for elimination in 2007. 1 Syphilis in pregnancy is not rare. Far more pregnant women have syphilis than human immunodeficiency virus (HIV) infection: 1.9 million (2008) and 1.49 million (2010), respectively. 2 The fraction of...

Dermatologists commonly find it difficult to diagnose syphilis, because of its protean clinical features. In cases of co-infection with human immunodeficiency virus (HIV) syphilis may present particularly unusual clinical features, further confounding the diagnosis. We report two cases of syphilis/HIV co-infection in Japanese patients showing uncommon skin features that made the diagnosis of sy...

background and objectives: intravenous drug using is a main risk factor for getting infected with hiv, hepatitis b and c viruses. the syphilis is a common infection. the aim of this study was to investigate the seroepidemiology of hiv, syphilis, hepatitis b and c among the intravenous drug users (idus) at loghman hakim hospital, tehran. materials & methods: a descriptive (cross- sectional) stud...

BACKGROUND The infection rate of syphilis in China has increased dramatically in recent decades, becoming a serious public health concern. Early prediction of syphilis is therefore of great importance for heath planning and management. METHODS In this paper, we analyzed surveillance time series data for primary, secondary, tertiary, congenital and latent syphilis in mainland China from 2005 t...

BACKGROUND The objective of this study was to examine the epidemiology of syphilis among high-risk socially marginalized populations in urban, coastal Peru, to quantify the prevalence of recent syphilis infection and identify risk factors. METHODS Survey data and serologic specimens were collected from a population-based sample of 3 populations: men who have sex with only men (MSOM), socially...

Syphilis is considered one of the greatest imitators which can mimic any skin disease. Keen examination together with a sound brain and high degree suspicion required for its diagnosis. Syphilis, sexually transmitted disease caused by spirochete Treponema pallidum pallidum, was more common during Second World War. Later, as human immunodeficiency virus cases increased, there increased,incidence...

Abstract A 59-year-old man was referred to an urgent skin cancer dermatology clinic with a 4-month history of multiple lesions on his trunk, arms and face. The were painful, increasing in size, bleeding oozing serous fluid. patient reported being otherwise systemically well, mild eczema background high alcohol intake. On examination, he had striking rash numerous large rupioid plaques thick cru...

BACKGROUND Effective implementation of rapid point of care tests (POCTs) for antenatal syphilis screening especially in settings where antenatal care attendance is high, can significantly increase screening coverage and treatment uptake. The operational challenges of introducing rapid syphilis POCTs at scale needs to be investigated. This study explores healthcare providers' experiences and cha...

After several years of steady decline, syphilis is reemerging globally as a public health hazard, especially among people living with human immunodeficiency virus (HIV). Syphilis resurgence is observed mainly in men who have sex with men (MSM), yet other transmission groups are affected too. In this manuscript, we study the factors associated with syphilis incidence in the Swiss HIV cohort stud...