the neuropsychiatric manifestations of systemic lupus erythematosus are frequent. one of the most serious presentations is convulsion. this study was carried out to evaluate the relation between convulsion and anti-dna antibody levels. an analytic, retrospective case-controlled study was carried out, with reference to 1001 recorded cases of systemic sle lupus erythematosus in lupus unit, rheuma...

this case report demonstrates fatal gastrointestinal vasculitis as a rare presentation of systemic lupus erythematosus. a 34-year-old woman presented with abdominal pain and diarrhea. anti nuclear antibody was positive and high titre of anti-ds dna antibody was also reported. treatment with corticosteroid and supportive cares were started; however, her condition worsened. eventually, she was co...

hemophagocytic syndrome (hps) is an uncommon manifestation in systemic lupus erythematosus (sle). clinical features of hps include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. hps comprises primary and reactive forms. herein, we describe a case of untreated sle with hps as one of the first manifestations of systemic lupus.

gastrointestinal (gi) and hepatic manifestations are not uncommon in patients with systemic lupus erythematosus (sle). they include nonspecific symptoms as well as serious, life-threatening complications necessitating urgent, aggressive therapy. in addition to direct involvement of the gi system by the disease, many drug-induced side effects and opportunistic infections have gi and hepatic mani...

conclusions silent ventricular systolic dysfunction was more common in the patients with sle than in the control group. newer echocardiographic techniques such as two-dimensional ste provide an earlier chance for the detection of subclinical lv systolic dysfunction. our findings were independent of the traditional risk factors. results the mean duration of sle was 5.5 ± 3.4 years in our patient...

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introduction mycobacterium tuberculosis (mtb) is one of the most common causes of disseminated granulomatous diseases especially in developing countries. case presentation we present a patient who had an unusual type of tuberculosis who was misdiagnosed with some other common diseases such as infective endocarditis and collagen vascular diseases. pathological examination helped us to make decis...

macrophage activating syndrome (mas) is a life-threatening disease seen in autoimmune diseases including lupus erythematosus, rheumatoid arthritis, still's disease, polyarteritis nodosa. it is characterized by fever, pancytopenia, liver failure, coagulopathy, and neurologic symptoms and high serum ferritin. a 27 yr. old female patient was admitted in shahid mostafa khomeini hospital (tehra...