OBJECTIVES To characterize challenges experienced during stages of female-to-male sex transition and investigate associations between transition-specific measures of psychosocial stress, nocturnal decline in ambulatory blood pressure (amBP), and changes in C-reactive protein (CRP) levels. METHODS For this biocultural study, 65 healthy transmen who were using testosterone (T) therapy participa...

Background: Infertility effects on psychological and emotional tension in couples and make severe stress in infertile men and women. Relaxation technique is one of the methods which reduce stress and balance human emotions. The purpose of this study was determination of relaxation effect on stress score in the infertile women and pregnancy test as outcome of their treatment. Materials and Metho...

OBJECTIVE Mental or emotional stress-induced ventricular arrhythmias and sudden cardiac death are thought to be mediated by the autonomic nervous system and ischemia. In the absence of ischemia, increased inhomogeneity of repolarization is thought to be important. We tested the hypotheses that in the absence of ischemia, mental stress may modulate repolarization by changing autonomic balance; a...

Restraint stress reduced blood alcohol levels in pregnant rats given a liquid alcohol diet. The male offspring prenatally exposed to both stress and alcohol failed to ejaculate spontaneously, although they copulated normally following exogenous testosterone (T) administration. Males prenatally exposed only to alcohol or only to stress showed no behavioral deficits. Adult serum T and luteinizing...

Suitable macroscopic quantities beyond effective elastic properties are used to assess the distribution of stress within a composite. The composite is composed of N anisotropic linearly elastic materials and the length scale of the microstructure relative to the loading is denoted by ε. The stress distribution function inside the composite λε(t) gives the volume of the set where the norm of the...

BACKGROUND Stress is thought to be abortogenic and psycho-neuro-immunological pathways have been suggested to be involved in triggering miscarriages. From experiments in pregnant mice exposed to stress some insights into the underlying mechanisms have been gained, delineating immunological imbalances as a cause of pregnancy failure. In order to test the validity of the conclusions drawn from mu...

Immobilization stress (IMO) induces a rapid increase in glucocorticoid secretion [in rodents, corticosterone CORT)] and this is associated with decreased circulating testosterone (T) levels. Nitric oxide (NO), a reactive free radical and neurotransmitter, has been reported to be produced at higher rates in tissues such as brain during stress. The biosynthesis of T is also known to be dramatical...

The NFAT5/TonEBP transcription factor, a recently identified rel/NF-kappaB family member, activates transcription of osmocompensatory genes in response to extracellular hyperosmotic stress. However, the function of NFAT5 under isosmotic conditions present in vivo remains unknown. Here we demonstrate that NFAT5 is necessary for optimal T cell development in vivo and allows for optimal cell growt...

Oxidative stress, biochemical and enzymological biomarkers were compared among rainbow trout, Oncorhynchus mykiss (Walbaum), brown trout, Salmo trutta (L.), and grayling, Thymallus thymallus (L.) to determine the mechanisms of hepatotoxicity caused by chloramine-T bath treatment. The fish were exposed to chloramine-T at a concentration of 9 g m for 20 min three times daily every three days. The...