Parthenolide, the principal component of sesquiterpene lactones present in medical plants such as feverfew (Tanacetum parthenium), has been reported to have anti-tumor activity. In this study, we evaluated the therapeutic potential of parthenolide against bladder cancer and its mechanism of action. Treatment of bladder cancer cells with parthenolide resulted in a significant decrease in cell vi...

Parthenolide is a major sesquiterpene lactone derived from feverfew (Tanacetum parthenium) with known anti-inflammatory activity. Moreover, the anticancer potential of this compound was suggested. In this study, we determined the effect of parthenolide on proliferation of three human cancer cell lines: human lung carcinoma (A549), human medulloblastoma (TE671), human colon adenocarcinoma (HT-29...

The essential oils obtained by hydrodistillation (HD), steam distillation (SD) and solvent free microwave extraction (SFME) from the stems and flowers of Tanacetum tenuisectum (Boiss.) Podl., which is endemic to Iran,were analyzed by GC and GC/MS.Camphor (26.9 %, 27.2% and 25.5%), borneol (12.6%, 11.5% and 7.6%) and 1, 8-cineole (7.9%, 13.2% and 11.3%) were the main constituents of the HD, SD a...