BACKGROUND Feverfew (Tanacetum parthenium L.), magnesium and coenzyme Q10 are frequently used for migraine prophylaxis. Supplementation with a fixed combination of these three agents (Antemig®, PiLeJe) was investigated in an observational study. METHODS Adult patients suffering from migraine according to the criteria of the International Headache Society were enrolled by general practitioners...

Parthenium (Parthenium hysterophorus L.) has become an invasive woody plant in recent times in many part of the world affecting the agricultural productivity. Hence we carried out to evaluate the effect of P. hysterophorus on germination and elongation of Onion (Allium cepa) and Bean (Phaseolus vulgaris). The plant extract prepared by the extractions of 1,2,4,8, and 16 gram powder in a 400ml of...

This paper describes the development of a normal-phase liquid chromatography ultraviolet-diode array detection method for the simultaneous quantification of parthenin and coronopilin in the leaves and flowers of Parthenium hysterophorous. The compounds were analyzed on a Merck Si60 silica column (5 µm, 250 × 4 mm) using an isocratic 15:85 mixture of isopropyl alcohol and hexane. The calibration...

Background and Aim: The aim of this study was to investigate the protective effects of Tanacetum parthenium extract (TPE) on lipid peroxidation and acute heart injury induced by carbon tetrachloride (CCl4) in rats. Materials and Methods: In an experimental study, 30 male Wistar rats were divided into 5 groups (n=6). Two of the groups were normal and damage control groups, other 3 groups were d...

Medicinal plants have been widely employed in treating various diseases for centuries and are still a major resource and repository that can be further exploited for a variety of infectious and non-infectious ailments. The popularity of medicinal herbs has grown significantly in recent years despite a dearth of information regarding their modes of action and continuing concerns over their effic...

Tanacetum santolinoides, Essential Oil Composition, n-Hexane-Ether Extract Composition The essential oil of the aerial parts of Tanacetum santolinoides was analyzed by capillary GLC and GLC-MS. Altogether 30 components were identified. The main constituents were thymol (18%), trans-thujone (17.5%), trans-chrysanthenyl acetate (13.2%), cis-chrysanthenyl acetate (9.2%), umbellulone (9.7%) and 1,8...

This review outlines the molecular events that accompany the anti-tumor action of parthenolide (PN). Parthenolide (PN) is naturally derived compound, isolated from plant Tanacetum parthenium. PN has been previously shown to withdraw cells from cell cycle or to promote cell differentiation, and finally to induce programmed cell death. Recent advances in molecular biology indicate that this sesqu...

Parthenium hysterophorus L., (Asteraceae) commonly known as parthenium weed, is a highly invasive plant that has become a problematic weed of pasture lands in Australia and many other countries around the world. For the management of this weed, an integrated approach comprising biological control and plant competition strategies was tested in southern central Queensland. Two competitive pasture...

Oxylipins are oxygenated derivatives of fatty acids and pivotal signaling molecules in plants and animals. Allene oxide synthase (AOS) is a key cytochrome P450 CYP74 enzyme involved in the biosynthesis of plant oxylipin jasmonates to convert 13(S)-hydroperoxide to allene oxide. Guayule (Parthenium argentatum) AOS, CYP74A2, was expressed in Escherichia coli. Protein was purified using affinity c...