PURPOSE The aim of this study is to ascertain the subsequent radiobiological impact of using a consensus guideline target volume delineation atlas. MATERIALS AND METHODS Using a representative case and target volume delineation instructions derived from a proposed IMRT rectal cancer clinical trial, gross tumor volume (GTV) and clinical/planning target volumes (CTV/PTV) were contoured by 13 ph...

Radiotherapy is a tumor treatment process using high dose of radiation. Hence, it is essential that radiotherapy is carefully planned with a Treatment Planning System (TPS). The first step in TPS is delineation that aims to get a better picture of the tumor and the target volume value. This research investigated volume target delineation for brain tumor against the MRI image of the head in axia...

The name “Brachytherapy” is derived from ancient Greek words for short distance (brachios) and treatment (therapy) and refers to the therapeutic use of encapsulated radionuclides placed within or close to the tumor. Brachytherapy (BT), used as an integral part of cancer treatment for almost a century, developed in last three decades a rapid growth with the development of afterloading devices an...

BACKGROUND In this study, we aimed to establish the rabbit VX2 limb tumor model, and then prepare a "necrotic zone" as a safe margin by volumetric modulated arc therapy and simultaneous integrated boost (VMAT-SIB) technique applied in the areas where the tumor is located adjacent to the bone (GTVboost area). MATERIAL AND METHODS Rabbits in the control group (n=10) were not treated, while thos...

BACKGROUND The aim of this study was to quantify the variability in spinal radiosurgery (SRS) planning practices between five international institutions, all member of the Elekta Spine Radiosurgery Research Consortium. METHODS Four institutions provided one representative patient case each consisting of the medical history, CT and MR imaging. A step-wise planning approach was used where, afte...

BACKGROUND AND PURPOSE Brachytherapy (BT) plays a crucial role in the management of invasive cervix cancer from stage I to IV. Intracavitary techniques are based on afterloading devices, with different types of applicators. CT and/or MRI compatible applicators allow a sectional image based approach with a better assessment of gross tumour volume (GTV) and definition and delineation of target vo...

AIMS To review the Batra Hospital and Medical Research Centre experience of using compensator-based intensity-modulated radiotherapy (IMRT) to treat head and neck cancer. MATERIALS AND METHODS Between October 2003 and August 2004, 18 patients underwent IMRT for head and neck cancer at our institution. IMRT was delivered using partial transmission high-resolution compensator blocks. RESULTS ...