نتایج جستجو برای: target genes
تعداد نتایج: 781140 فیلتر نتایج به سال:
In quantitative real-time PCR, the mRNA level can be quantified in relative terms based on the expression ratio of mRNAs of the target gene and an internal reference gene. Since, an internal standard should be expressed at a constant level among different tissues of an organism at all stages of development, and should be unaffected by the experimental treatment, the stability of different refer...
Background: Epithelial ovarian cancer (EOC) is one of the most lethal gynecological malignancy worldwide. Although the majority of EOC patients achieve clinical remission after induction therapy, over 80% relapse and succumb to the chemoresistant disease. Previous investigations have demonstrated the association of epidermal growth factor receptor (EGFR) with resistance to cytotoxic chemotherap...
Different characters influence the marketing of rice in which aroma, amylose content, gelatinization temperature, gel consistency and grain shape are the most important ones. Two local quality (Shastak and Domsia) and two improved rice varieties (Nemat and Fajrr) were used to pyramid the qualitative genes into new released Ghaem variety through classical methods and marker aided selection. ...
background and objectives: staphylococcus aureus ( s. aureus ) nasal carriage may be responsible for some serious infections in hemodialyzed patients. the main target of this study was to estimate the prevalence of s. aureus nasal carriage in hemodialysis outpatients and medical staff in hemodialysis centers specifically in fez region. the second target is to identify the risks of colonization,...
Background: The stress is one of main factors effects on production system. Several factors (both genetic and environmental elements) regulate immune response to stress. Objectives: In order to determine the major immune system regulatory genes underlying stress responses, a learning Bayesian network approach for those regulatory genes was applied to RNA-...
optimization of gene transfection in murine myeloma cell lines using different transfection reagents
purification and isolation of cellular target proteins for monoclonal antibody (mab) production is a difficult and time-consuming process. immunization of mice with murine cell lines stably transfected with genes coding for xenogenic target molecules is an alternative method for mouse immunization and mab production. here we present data on transfection efficiency of some commercial reagents us...
Lymphomas are solid tumors of immune system and Non-Hodgkin Lymphomas (NHL) is the most prevalent lymphomas; with wide ranges of histological and clinical features, it is so difficult to identify them. Herein, various bioinformatics tools (such as gene differential expressions, epigenetics and protein analysis) employed to find new treatment approach for NHL based on gene expression variation b...
cancer incidence is projected to increase in the future and an effectual preventive strategy is required to face this challenge. alteration of dietary habits is potentially an effective approach for reducing cancer risk. assessment of biological effects of a specific food or bioactive component that is linked to cancer and prediction of individual susceptibility as a function of nutrient-nutrie...
background: in gene therapy, the use of rna molecules as therapeutic agents has shown advantages over plasmid dna, including higher levels of safety. however, transient nature of rna has been a major obstacle in application of rna in gene therapy. methods: here, we used the internal ribosomal entry site of encephalomyocarditis virus and the 3’ non-translated region of poliovirus to design an en...
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