نتایج جستجو برای: targeted gene delivery

تعداد نتایج: 1430970  

Journal: :iranian biomedical journal 0
مهدی محمودی mehdi mahmoodi james v. gardiner عباس لطفی abbas s. lotfi stephen r. bloom

polyethylenimine (pei) has been proposed as a non-viral vector, and has been successfully used to transfer reporter genes into the central nervous system (cns), kidneys, and lungs of adult mice. neuropeptide y (npy) is a peptide expressed in the hypothalamus and is important in the regulation of body weight. using pei combined with stereotactic microinjection, we have successfully transferred c...

Journal: :nanomedicine journal 0
azadeh hashem nia pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran school of sciences, department of chemistry, ferdowsi university of mashhad, mashhad, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (mashhad university of medical sciences) hossein eshghi school of sciences, department of chemistry, ferdowsi university of mashhad, mashhad, iranسازمان اصلی تایید شده: دانشگاه فردوسی (ferdowsi university) khalil abnous pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (mashhad university of medical sciences) mohammad ramezani pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (mashhad university of medical sciences)

objective(s): carbon nanotube (cnt) has been widely applied at molecular and cellular levels due to its exceptional properties. studies based on conjugation of cnts with biological molecules indicated that biological activity is preserved. polyethylenimine (pei) is explored in designing novel gene delivery vectors due to its ability to condense plasmid dna through electrostatic attraction. in t...

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