BACKGROUND Postmenopausal estrogen replacement therapy (ERT) has an antioxidant effect that opposes the oxidation of LDL particles. Oral ERT-induced increases in plasma triglyceride, however, decrease LDL particle size, which may counteract this antioxidant effect. Because transdermal ERT decreases plasma triglyceride, it may not decrease LDL particle size and may preserve estrogen's antioxidan...

AIM To determine the existence and level of oxidative stress caused by lipid peroxidation in pregnancy. METHODS The research was conducted as prospective examination that included 60 healthy women (age 18-45). The women included in the examination were divided into two groups. The group I (N-31) included women in the first trimester of normal, healthy pregnancy. The group II included healthy ...

and Implications Irradiation dose had a significant effect on the production of volatiles in both vacuumand aerobic-packaged cooked pork sausage, but its effect on the thiobarbituric acid reactive substances (TBARS) values was minor. Storage increased the production of volatiles and changed the composition of volatiles only in aerobic-packaged sausage. Among the volatile components, 1-heptene a...

UNLABELLED In recent years researchers have made a lot of studies to determine the molecular and neurochemical mechanisms which are the basis of depressive disorders. Apoptosis is a cause of the limbic system neuronal cells defect in patients suffering from depression. The antioxidant system is the best known molecular mechanism which protects the cells from apoptosis. This system exists inside...

Exercise, alone or combined with changes in lifestyle, can prevent or reduce the need for pharmacotherapy in patients with compromised endothelium-dependent function. The aim of this study was to examine the protective effect of aerobic exercise against (L-NAME)-kidney damage in male rats induced by Nω-nitro-L-arginine methyl ester (L-NAME). L-NAME was administered to rats intraperitoneally in ...

This work presents an evaluation of the impact of physical exercise of the upper limbs in patients with muscular atrophy in the lower limbs by analysis of specific biomarkers.It is a cross-sectional study. Patients were recruited using convenience sampling: control group (C: n = 12) and two groups of wheelchair users: non-athletes (NAth: n = 12) and athletes (Ath: n = 13, professional basketbal...

Objective: of this study was to determine changes in oxidative indices in tissues of exercised rats fed diet fortified with choline, carnitine and caffeine; and relate to those reported in humans. Methods: 7-week old male Sprague-Dawley rats were studied for five weeks. Diets were supplemented with choline, carnitine and caffeine and rats were either exercised or not during the last 2 weeks of ...

Oxidant generation in anoxia-reoxygenation and ischemia-reperfusion was compared in isolated rat lungs. Anoxia-reoxygenation was produced by N2 ventilation followed by O2 ventilation. After anoxia, lung ATP content was decreased by 59%. Oxygenated ischemia was produced by discontinuing perfusion while ventilation with O2 was maintained. With anoxia-reoxygenation, oxidant generation, evaluated b...

The aim of the study was to assess the markers of oxidant-antioxidant status in excess body mass index (BMI) persons with and without the obstructive sleep apnea syndrome (OSAS). In overweight (BMI-1: 25.0-29.9 kg/m(2)) control and OSAS and obese (BMI-2: 30.0-34.9 kg/m(2)) control and OSAS subjects with no acute or chronic disorder the following markers were determined: concentration of plasma ...

Discussion continues as to whether de novo hypertension in pregnancy with significant proteinuria (pre-eclampsia; PE) and non-proteinuric new hypertension (gestational hypertension; GH) are parts of the same disease spectrum or represent different conditions. Non-pregnant hypertension, pregnancy and PE are all associated with oxidative stress. We have established a 6 weeks postpartum clinic for...