Oxidized low density lipoproteins (LDL) are highly suspected of initiating the atherosclerosis process. Thyroid hormones and structural analogues have been reported to protect LDL from lipid peroxidation induced by Cu2+ or the free radical generator 2,2'-azobis-'2-amidinopropane' dihydrochloride in vitro. We have examined the effects of thyroid compounds on macrophage-induced LDL oxidation. Hum...

Objective. The objective of this work was to study the risk factors of ischaemic heart disease (IHD) in rural populations of the Nilgiris, south India, with stress on the various social habits and oxidant stress. Methods. A total of 72 patients with cardiovascular disease (CVD) and 12 healthy volunteers were screened. Forty-seven patients with CVD (intervention group) and 10 healthy volunteers ...

OBJECTIVES Previous research on a group of workers occupationally exposed to styrene, ethylene glycol, toluene, p-xylene and their mixture showed elevated levels of the main products of lipid peroxidation: malondialdehyde and 4-hydroxynonenal (MDA+,4-HNE) in plasma [1]. Moreover, an earlier in vitro study indicated a synergistic interaction between styrene and ethylene glycol on lipid peroxidat...

Oxidative stress has been pointed as an important molecular mechanism for liver injury in methylmercury (MeHg) poisoning. Ebselen, a seleno-organic compound that possesses anti-oxidant properties, is a useful therapeutic agent used in clinical situations involving oxidative stress. Here, we examined the possible in vivo protective effect of ebselen against the pro-oxidative effects of MeHg in l...

Commercial samples of beef and turkey meat were prepared by commonly used cooking methods with standard cooking times: (1) broiled at 200°C for 10min, (2) broiled at a medium temperature (140°C) for 10min, (3) cooked by microwave (MW) for 3min and then grilled (MW/grill) for 7min, (4) cooked in a domestic microwave oven for 10min, and (5) boiled in water for 10min. The raw and cooked meats were...

Raw pulses as extenders in meat preparations result oxidative processes. The effects of using a raw chickpea paste (CP; 1/2; chickpea/water) pork patties were evaluated. In first experiment, prepared with increasing levels CP (0 to 25%); second (25%) and without (controls) kept at 4 °C or 22 for 18 h before patty production; third chitosan, garlic, cumin (from 0.5 2%) added controls, their anti...

Temperature and time are two critical parameters in sous vide cooking which directly affect eating quality characteristics food safety. This study aimed to evaluate physicochemical microbiological properties of chicken breast fillets cooked at twelve different combinations temperature (60, 70, 80 °C) 90, 120, 150 min). The results showed that played a major role the moisture content, loss, pH, ...

OBJECTIVE To determine the effects of zinc (Zn) supplementation on oxidative stress in persons with type 2 diabetes mellitus (type 2 DM). DESIGN Tunisian adult subjects with HbA1c >7.5% were supplemented for six months with 30 mg/day of Zn as Zn gluconate or placebo. The effects of supplementation on plasma zinc (Zn), copper (Cu), urinary Zn, plasma thiobarbituric acid reactive substances (TB...

OBJECTIVE Systemic oxidative stress is associated with insulin resistance and obesity. We tested the hypothesis that systemic oxidative stress is linked to lower aerobic capacity and skeletal muscle dysfunction in metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS The incremental exercise testing with cycle ergometer was performed in 14 male patients with MetS and 13 age-, sex-, and activ...

Three experiments were conducted to develop a sensitive and reliable fluorometric thiobarbituric acid (TBA) reactive substances (TBARS) method to determine lipid oxidation products in meat. The first study was conducted to find the optimum sample preparation conditions for meat in the fluorometric method. The second study was to compare the original and the modified methods by using meat and bl...